Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 9/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146423 | 0.86 | ACHE (0.54) | ACHEBCHEHPGD | |
| SCHEMBL7044948 | 0.85 | ACHE (0.50) | ACHEMEN1NPC1KMT2ABCHE | |
| Water SCHEMBL436371 | 0.85 | ACHE (0.53) | ACHEBCHEHPGD | |
| Ammonia Solution, Strong SCHEMBL30096047 | 0.85 | ACHE (0.53) | ACHEBCHEHPGD | |
| Ammonia Solution, Strong SCHEMBL28899074 | 0.85 | ACHE (0.53) | ACHEBCHEHPGD | |
| SCHEMBL17187153 | 0.83 | ACHE (0.53) | ACHEBCHE | |
| SCHEMBL5546357 | 0.76 | ATM (0.41) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3194487 | 0.75 | ACHE (0.54) | ACHEKDM4EMEN1KMT2ABCHE | |
| SCHEMBL5540749 | 0.75 | ACHE (0.49) | ACHEKDM4ELMNAHTTHPGD | |
| SCHEMBL31305314 | 0.73 | BCHE (0.66) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806089-B1 | QUANTITATIVE ANALYSIS; DOES NOT REQUIRE THE SENSING FLUOROPHORE TO DISPLAY A CHANGE IN LIFETIME; SELF-CALIBRATING | UNIVERSITY OF MARYLAND, BALTIMORE | 2004-10-19 | — | — | US | claimed |