⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057836 | 0.81 | ALDH1A1 (0.36) | — | |
| SCHEMBL7051625 | 0.77 | — | — | |
| SCHEMBL507408 | 0.75 | — | — | |
| SCHEMBL5187333 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL10058332 | 0.75 | — | — | |
| SCHEMBL161314 | 0.75 | LMNA (0.42) | — | |
| SCHEMBL25243423 | 0.73 | — | — | |
| SCHEMBL572712 | 0.73 | — | — | |
| SCHEMBL20589984 | 0.73 | — | — | |
| SCHEMBL436900 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846419-A2 | ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006086449-A2 | ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-17 | — | — | WO | disclosed |