SCHEMBL5541192

SCHEMBL5541192

CCC(=O)Nc1cccc2c1C(=O)c1cccc(NC(=O)CS)c1C2=O

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.62
HPGD P15428 1/20 0.62
TERT O14746 13/20 0.59
MEN1 O00255 1/20 0.54
ALDH1A1 P00352 1/20 0.54
POLB P06746 1/20 0.54
GAA P10253 1/20 0.54
DNMT1 P26358 1/20 0.54
RAD52 P43351 1/20 0.54
SMARCA2 P51531 1/20 0.54
KMT2A Q03164 1/20 0.54
MAOA P21397 1/20 0.54
PTPRC P08575 1/20 0.48
PTPN13 Q12923 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1679982 0.92 TERT (0.63) MAPTTERTMEN1ALDH1A1POLB
SCHEMBL6366579 0.92 TERT (0.68) MAPTHPGDTERTMEN1ALDH1A1
SCHEMBL5541185 0.88 TERT (0.57) MAPTHPGDTERTMEN1ALDH1A1
SCHEMBL8602265 0.88 MAOA (0.69) MAPTHPGDTERTMEN1ALDH1A1
SCHEMBL1679959 0.88 TERT (0.64) MAPTTERTMEN1ALDH1A1POLB
SCHEMBL15267669 0.85 TERT (0.56) MAPTTERTMEN1ALDH1A1POLB
SCHEMBL7929921 0.82 CYP1A2 (0.57) MAPTTERTMEN1ALDH1A1POLB
SCHEMBL12111918 0.81 TERT (0.60) MAPTHPGDTERTMEN1ALDH1A1
SCHEMBL9510413 0.80 TERT (0.73) MAPTTERTMEN1ALDH1A1POLB
SCHEMBL19102201 0.80 APEX1 (0.56) MAPTTERTMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE44510-E1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2013-09-24 US disclosed
US-8173842-B2 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2012-05-08 US disclosed