SCHEMBL5541969

SCHEMBL5541969

NC(c1cc[c]cc1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.48
F2 P00734 1/20 0.48
HTR2A P28223 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38
LMNA P02545 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminodiphenylmethane SCHEMBL8518249 0.87 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL7841 0.84 DPP4 (0.65) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL2408346 0.81 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL11480062 0.81 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL11478580 0.81 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL8686295 0.81 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL9596876 0.81 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL6970159 0.81 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL1764753 0.81 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL28527476 0.81 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107501294-B Rapamycin guanidine derivative and purposes 福建省微生物研究所 2019-09-10 CN disclosed
CN-104205472-B Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same 三菱化学株式会社 2017-04-12 CN disclosed
CN-104059173-B A kind of supported late transition metal catalyst for vinyl polymerization 中国石油化工股份有限公司 2016-09-21 CN disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
CN-101255170-A 2,3-dihydroimidazo[2,1-b]oxazole compound OTSUKA PHARMA CO LTD (JP) 2008-09-03 CN disclosed
CN-101172981-A 2,3-dihydroimidazo[2,1-b]oxazole compound OTSUKA PHARMA CO LTD (JP) 2008-05-07 CN disclosed
CN-100366624-C 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds OTSUKA PHARMA CO LTD (JP) 2008-02-06 CN disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US disclosed
CN-1705670-A 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds OTSUKA PHARMA CO LTD (JP) 2005-12-07 CN disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed
CN-1246885-A fluorescent material and use thereof CIBA SC HOLDING AG (CH) 2000-03-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 DPP4 3965/4885F2 4718/4885HTR2A 4120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.