Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | CBX7 | O95931 | 3/20 | 0.56 |
| ▸ | CDYL | Q9Y232 | 3/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.53 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995838 | 0.85 | HPGD (0.71) | HPGDMAPK1TSHRUSP2ALDH1A1 | |
| SCHEMBL5537191 | 0.82 | ALDH1A1 (0.68) | HPGDMAPK1TSHRUSP2ALDH1A1 | |
| SCHEMBL27210129 | 0.81 | HTT (0.44) | HPGDTSHRALDH1A1HTTLMNA | |
| SCHEMBL29811259 | 0.81 | HTT (0.44) | HPGDTSHRALDH1A1HTTLMNA | |
| SCHEMBL5548457 | 0.81 | ALDH1A1 (0.70) | HPGDMAPK1TSHRUSP2ALDH1A1 | |
| SCHEMBL2947194 | 0.80 | HPGD (0.73) | HPGDMAPK1TSHRUSP2ALDH1A1 | |
| SCHEMBL14667473 | 0.79 | HPGD (0.58) | HPGDMAPK1TSHRUSP2ALDH1A1 | |
| SCHEMBL4412637 | 0.79 | MEN1 (0.63) | HPGDMAPK1TSHRUSP2ALDH1A1 | |
| SCHEMBL4414345 | 0.79 | HPGD (1.00) | HPGDMAPK1TSHRUSP2ALDH1A1 | |
| SCHEMBL6717405 | 0.78 | HPGD (0.66) | HPGDMAPK1TSHRUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | HPGD 3159/4885MAPK1 1392/4885TSHR 319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.