Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CDYL2 | Q8N8U2 | 3/20 | 0.60 |
| ▸ | CDYL | Q9Y232 | 3/20 | 0.60 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 3/20 | 0.60 |
| ▸ | CBX7 | O95931 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5283365 | 0.85 | HPGD (0.62) | HPGDLMNASMN1; SMN2KDM4EPOLB | |
| SCHEMBL10444126 | 0.85 | ALDH1A1 (0.64) | HPGDLMNASMN1; SMN2USP2TSHR | |
| SCHEMBL10443548 | 0.85 | MAPK1 (0.68) | HPGDSMN1; SMN2POLBRECQLMAPK1 | |
| SCHEMBL13995838 | 0.83 | HPGD (0.71) | HPGDLMNASMN1; SMN2POLBCDYL2 | |
| SCHEMBL6300684 | 0.82 | KDM4E (0.59) | HPGDLMNASMN1; SMN2KDM4EPOLB | |
| SCHEMBL5286548 | 0.82 | HPGD (0.58) | HPGDLMNAPOLBCDYL2CDYL | |
| SCHEMBL4427310 | 0.82 | LMNA (0.71) | HPGDLMNAPOLBCDYL2CDYL | |
| SCHEMBL14564389 | 0.81 | MIF (0.56) | POLBRECQLALDH1A1KMT2AMEN1 | |
| SCHEMBL10621377 | 0.81 | MIF (0.57) | SMN1; SMN2KDM4ECDYL2CDYLCDY1; CDY1B | |
| SCHEMBL11136935 | 0.81 | ALDH1A1 (0.69) | HPGDSMN1; SMN2POLBUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244763-B2 | Compounds that modulate PPAR activity and methods of preparation | WARNER LAMBERT COMPANY LLC (US) | 2007-07-17 | — | — | US | disclosed |
| US-7244763-B2 | Compounds that modulate PPAR activity and methods of preparation | WARNER LAMBERT COMPANY LLC (US) | 2007-07-17 | — | — | US | disclosed |
| US-20040214832-A1 | Piperazine derivative renin inhibitors | WARNER-LAMBERT COMPANY LLC | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214832-A1 | Piperazine derivative renin inhibitors | REN, ACE, AGTR2 | HPGD 256/4885LMNA 2783/4885SMN1; SMN2 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.