SCHEMBL5543077

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5541848	0.86	TSHR (0.47)	TSHRTAS1R3TAS1R1TAS1R2ERCC5
	SCHEMBL2094929	0.82	TSHR (0.59)	TSHRTAS1R3TAS1R1TAS1R2ERCC5
	SCHEMBL16952644	0.75	TSHR (0.55)	TSHRTAS1R3TAS1R1TAS1R2ERCC5
	SCHEMBL16956641	0.73	TSHR (0.64)	TSHRTAS1R3TAS1R1TAS1R2ERCC5
	SCHEMBL16956594	0.71	TSHR (0.50)	TSHRTAS1R3TAS1R1TAS1R2ERCC5
	SCHEMBL5536983	0.70	SMN1; SMN2 (0.50)	TSHRERCC5FEN1CYP2C9ALDH1A1
	SCHEMBL14604999	0.69	CES2 (0.43)	TSHRERCC5FEN1TP53ALDH1A1
	SCHEMBL16230454	0.69	ALDH1A1 (0.56)	TSHRALDH1A1MAPT
	SCHEMBL24070109	0.69	TSHR (0.48)	TSHRTAS1R3TAS1R1TAS1R2ERCC5
	SCHEMBL30209733	0.69	TSHR (0.48)	TSHRTAS1R3TAS1R1TAS1R2ERCC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.