SCHEMBL5543392

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4261942	0.89	RIPK1 (0.47)	HTR2AHRH1RIPK1TAAR1AOC3
	SCHEMBL5543183	0.80	CA1 (0.38)	HTR2AHRH1CYP3A4CHRM2ADRA2A
	SCHEMBL2073609	0.78	TAAR1 (0.57)	RIPK1TAAR1AOC3ALDH1A1TRPA1
	SCHEMBL9572633	0.77	RIPK1 (0.48)	RIPK1TAAR1AOC3LMNATRPA1
	SCHEMBL7351847	0.77	AOC3 (0.60)	HTR2AHRH1RIPK1TAAR1AOC3
	SCHEMBL5536705	0.76	ALDH1A1 (0.41)	ALDH1A1HPGD
	SCHEMBL5543402	0.76	HTR2A (0.44)	HTR2AHRH1RIPK1TAAR1AOC3
	SCHEMBL8196236	0.76	HRH1 (0.55)	HTR2AHRH1CYP3A4CHRM2HTR1A
	SCHEMBL9052651	0.74	MTOR (0.59)	CYP3A4LMNAALDH1A1ALOX15RAB9A
	SCHEMBL1046087	0.74	RIPK1 (0.53)	HTR2AHRH1RIPK1TAAR1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.