Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.79 |
| ▸ | MAPT | P10636 | 7/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.79 |
| ▸ | HPGD | P15428 | 7/20 | 0.79 |
| ▸ | TP53 | P04637 | 6/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.79 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.79 |
| ▸ | BLM | P54132 | 3/20 | 0.79 |
| ▸ | USP2 | O75604 | 1/20 | 0.79 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.79 |
| ▸ | RAB9A | P51151 | 8/20 | 0.76 |
| ▸ | NPC1 | O15118 | 7/20 | 0.76 |
| ▸ | POLB | P06746 | 4/20 | 0.76 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.76 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Genistein SCHEMBL7563328 | 0.90 | SMN1; SMN2 (0.89) | SMN1; SMN2MAPTALDH1A1HPGDTP53 | |
| SCHEMBL10623004 | 0.89 | SMN1; SMN2 (0.94) | SMN1; SMN2MAPTALDH1A1HPGDTP53 | |
| 5,7-Dihydroxyisoflavone SCHEMBL1586459 | 0.89 | MEN1 (1.00) | SMN1; SMN2MAPTALDH1A1HPGDTP53 | |
| Genistein SCHEMBL5801778 | 0.88 | SMN1; SMN2 (0.84) | SMN1; SMN2MAPTALDH1A1HPGDTP53 | |
| Genistein SCHEMBL554056 | 0.87 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1HPGDTP53 | |
| Genistein SCHEMBL19166 | 0.87 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1HPGDTP53 | |
| Genistein SCHEMBL29352944 | 0.87 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1HPGDTP53 | |
| Daidzein SCHEMBL2025991 | 0.86 | KDM4E (0.86) | SMN1; SMN2MAPTALDH1A1HPGDTP53 | |
| Genistein SCHEMBL830735 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTALDH1A1HPGDTP53 | |
| Genistein SCHEMBL551801 | 0.86 | MAPT (0.97) | SMN1; SMN2MAPTALDH1A1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116987747-A | Preparation method and application of extracellular polysaccharide based on monascus induced by genistein | 南昌大学 | 2023-11-03 | — | — | CN | claimed |
| WO-2020161522-A1 | FIBER-BASED COMPOSITION | THD S.P.A. (IT) | 2020-08-13 | — | — | WO | claimed |
| US-10610563-B2 | Use of ubiquitin-proteasome system inhibitors for treatment of tumors associated with neurofibromatosis type-2 | BIOXCEL CORPORATION (US) | 2020-04-07 | — | — | US | claimed |
| EP-2603222-B1 | COMBINATORY CANCER TREATMENT | UNIV MONTREAL (CA) | 2018-10-17 | — | — | EP | claimed |
| US-20170360872-A1 | USE OF UBIQUITIN-PROTEASOME SYSTEM INHIBITORS FOR TREATMENT OF TUMORS ASSOCIATED WITH NEUROFIBROMATOSIS TYPE-2 | BIOXCEL CORPORATION (US) | 2017-12-21 | — | — | US | claimed |
| EP-2709629-B1 | NOVEL CANCER THERAPIES AND METHODS | NUBER ULRIKE (SE) | 2017-10-11 | — | — | EP | claimed |
| EP-3224263-A1 | USE OF UBIQUITIN-PROTEASOME SYSTEM INHIBITORS FOR TREATMENT OF TUMORS ASSOCIATED WITH NEUROFIBROMATOSIS TYPE-2 | Bioxcel Corporation (US) | 2017-10-04 | — | — | EP | claimed |
| US-9429574-B2 | Cancer therapies and methods | NUBER ULRIKE (SE) | 2016-08-30 | — | — | US | claimed |
| CN-105777692-A | Method for extracting and determining soybean isoflavones | 河南省农业科学院芝麻研究中心 | 2016-07-20 | — | — | CN | claimed |
| WO-2016085943-A1 | USE OF UBIQUITIN-PROTEASOME SYSTEM INHIBITORS FOR TREATMENT OF TUMORS ASSOCIATED WITH NEUROFIBROMATOSIS TYPE-2 | RASTELLI, LUCA (US) | 2016-06-02 | — | — | WO | claimed |
| EP-2603222-A1 | COMBINATORY CANCER TREATMENT | UNIVERSITE DE MONTREAL (CA) | 2013-06-19 | — | — | EP | claimed |
| WO-2012164234-A1 | NOVEL TREATMENTS | MD PHARMA AB (SE) | 2012-12-06 | — | — | WO | claimed |
| WO-2012156463-A1 | NOVEL CANCER THERAPIES AND METHODS | NUBER ULRIKE (SE) | 2012-11-22 | — | — | WO | claimed |
| WO-2012019284-A1 | COMBINATORY CANCER TREATMENT | UNIVERSITE DE MONTREAL (CA) | 2012-02-16 | — | — | WO | claimed |
| CN-101795699-A | Fructus Lycii and inflammation | NESTEC SA | 2010-08-04 | — | — | CN | claimed |
| EP-1143988-B1 | COMPOSITION COMPRISING SOY PROTEIN, DIETARY FIBRES AND A PHYTOESTROGEN COMPOUND AND USE THEREOF IN THE PREVENTION AND/OR TREATMENT OF TYPE 2 DIABETES, THE METABOLIC SYNDROME AND ASSOCIATED CARDIOVASCULAR DISEASES | NUTRI PHARMA AS (NO) | 2004-02-18 | — | — | EP | claimed |
| EP-1133308-B1 | COMPOSITION COMPRISING SOY PROTEIN, DIETARY FIBRES AND A PHYTOESTROGEN COMPOUND AND USE THEREOF IN THE PREVENTION AND/OR TREATMENT OF CARDIOVASCULAR DISEASES | NUTRI PHARMA AS (NO) | 2003-11-12 | — | — | EP | claimed |
| US-6596289-B1 | Knitted garment of cotton, nylon or polyester adapted for tight fitting; contains polyimine which partially decomposes from exposure to skin pH, moisture and/or heat releasing ascorbic acid, lipoic acid and/or isoflavones | PUGLIESE PETER T (US) | 2003-07-22 | — | — | US | claimed |
| EP-1133307-B1 | USE OF A COMPOSITION COMPRISING SOY PROTEIN, DIETARY FIBRES AND A PHYTOESTROGEN COMPOUND IN THE PREVENTION AND/OR TREATMENT OF PULMONARY DISEASES | NUTRI PHARMA AS (NO) | 2003-06-11 | — | — | EP | claimed |
| EP-1038531-A2 | A composition comprising soybean isoflavones and a method for the production thereof | Ajinomoto Co., Inc. (JP) | 2000-09-27 | — | — | EP | claimed |