Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.84 |
| ▸ | MAPT | P10636 | 9/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.84 |
| ▸ | HPGD | P15428 | 8/20 | 0.84 |
| ▸ | NPC1 | O15118 | 8/20 | 0.84 |
| ▸ | RAB9A | P51151 | 8/20 | 0.84 |
| ▸ | TP53 | P04637 | 7/20 | 0.84 |
| ▸ | MEN1 | O00255 | 6/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.84 |
| ▸ | POLB | P06746 | 5/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.84 |
| ▸ | MAOA | P21397 | 4/20 | 0.84 |
| ▸ | MAOB | P27338 | 4/20 | 0.84 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.84 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.84 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.84 |
| ▸ | LMNA | P02545 | 3/20 | 0.84 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.84 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Genistein SCHEMBL554056 | 0.92 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| Genistein SCHEMBL19166 | 0.92 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| Genistein SCHEMBL29352944 | 0.92 | MAPT (1.00) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL14338667 | 0.91 | XDH (0.70) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| Formononetin SCHEMBL4223418 | 0.91 | MAPT (0.83) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| Formononetin SCHEMBL6312014 | 0.91 | MAPT (0.83) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| Genistein SCHEMBL551801 | 0.90 | MAPT (0.97) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| Genistein SCHEMBL551402 | 0.90 | MAPT (0.97) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| Genistein SCHEMBL38650814 | 0.90 | MAPT (0.97) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 | |
| Genistein SCHEMBL551449 | 0.90 | MAPT (0.97) | SMN1; SMN2MAPTALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655292-A | Cellular biologicals and therapeutic uses thereof | 旗舰先锋创新V股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| WO-2006091187-A1 | ISOFLAVONOIDS FOR PREVENTING RADIATION- AND CHEMOTHERAPY- INDUCED WEIGHT LOSS | LANDAUER MICHAEL R (US) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006067824-A1 | PASTA WITH IMPROVED DIGERIBILITY COMPRISING ISOFLAVONES | ALIVERIS S.P.A. (IT) | 2006-06-29 | — | — | WO | disclosed |
| US-7056952-B1 | for example, 3'-hydroxy-dihydrodaidzein, 5-hydroxy-O-demethylangolesin; for treating hormone dependent conditions and other diseases and disorders; anticarcinogenic agents | G.J. CONSULTANTS PTY. LTD. (AU) | 2006-06-06 | — | — | US | disclosed |
| US-20050031766-A1 | Miso with good flavor containing high amount of isoflavone compounds | MARUKOME CO., LTD. (JP) | 2005-02-10 | — | — | US | disclosed |
| US-6849281-B2 | Food product suitable for reducing low density lipoprotein cholesterol levels | UNILEVER BESTFOODS, NORTH AMERICA, A DIVISION OF CONOPCO, INC. (US) | 2005-02-01 | — | — | US | disclosed |
| CN-1120163-C | Soybean isoflavone and its prepn process with macroporous adsorption resin | CHINA FOOD FERMENTATION INDUST (CN) | 2003-09-03 | — | — | CN | disclosed |
| EP-1159963-A1 | Composition for and method of preventing or treating breast cancer | Protein Technologies International, Inc. (US) | 2001-12-05 | — | — | EP | disclosed |
| US-20010047033-A1 | Composition for and method of preventing or treating breast cancer | PROTEIN TECHNOLOGIES INTERNATIONAL, INC. | 2001-11-29 | — | — | US | disclosed |
| US-6300367-B1 | Composition for and method of preventing or treating breast cancer | PROTEIN TECHNOLOGIES INTERNATIONAL, INC. | 2001-10-09 | — | — | US | disclosed |
| WO-2001072126-A1 | PEA AND LENTIL PRODUCTION-ENHANCING COMPOSITIONS AND METHOD USING SAME | BIOS AGRICULTURE INC. (CA) | 2001-10-04 | — | — | WO | disclosed |