SCHEMBL5543628

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5537278	0.93	CHRM1 (0.52)	CHRM1HTR2AMCHR1CNR1ALDH1A1
	SCHEMBL3246568	0.89	GPR84 (0.46)	CHRM1HTR2AMCHR1CNR1LMNA
	SCHEMBL5543723	0.82	ALDH1A1 (0.57)	ALDH1A1MAPTMEN1KMT2APIK3CD
	SCHEMBL5539704	0.82	GPR84 (0.50)	CHRM1HTR2AMCHR1CNR1ALDH1A1
	SCHEMBL5543706	0.81	CHRM1 (0.39)	CHRM1HTR2AMCHR1CNR1ALDH1A1
	Hydrochloric Acid SCHEMBL6419975	0.81	ALDH1A1 (0.59)	CHRM1HTR2AMCHR1CNR1ALDH1A1
	SCHEMBL22894161	0.79	CHRM1 (0.56)	CHRM1HTR2AMCHR1CNR1ALDH1A1
	SCHEMBL4827710	0.79	L3MBTL1 (0.55)	ALDH1A1MAPTMEN1KMT2APIK3CD
	SCHEMBL3245776	0.78	MEN1 (0.56)	ALDH1A1LMNAMAPTMEN1KMT2A
	SCHEMBL5541923	0.78	TAAR1 (0.49)	CNR1ALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.