⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114535 | 0.79 | TRPA1 (0.42) | — | |
| SCHEMBL31055736 | 0.78 | LMNA (0.44) | — | |
| SCHEMBL8217394 | 0.78 | LMNA (0.44) | — | |
| SCHEMBL28823547 | 0.78 | — | — | |
| SCHEMBL207316 | 0.78 | — | — | |
| SCHEMBL1035353 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL1589395 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL2037821 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL20430118 | 0.75 | CD44 (0.50) | — | |
| SCHEMBL16131275 | 0.75 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12594282-B2 | Use of small molecule compounds in the treatment of diseases mediated by lung epithelial cell injury and/or vascular endothelial cell injury | GUANGZHOU CELLPROTEK PHARMACEUTICAL CO., LTD. (CN) | 2026-04-07 | — | — | US | disclosed |
| CN-120078776-A | Application of pioglitazone combined with ligustilide in preventing and treating metabolic-related fatty liver fibrosis | 北京中医药大学 | 2025-06-03 | — | — | CN | disclosed |
| WO-2025072861-A1 | CLEAVABLE CYCLIC LOOP NUCLEOTIDES FOR NANOPORE SEQUENCING | ILLUMINA, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| US-20250109434-A1 | CLEAVABLE CYCLIC LOOP NUCLEOTIDES FOR NANOPORE SEQUENCING | ILLUMINA, INC. (US) | 2025-04-03 | — | — | US | disclosed |
| CN-116327709-B | Preparation method and application of Cu-based nano-carrier with multiple stimulus response degradability | 桂林医学院 | 2025-01-07 | — | — | CN | disclosed |
| CN-118873568-A | Pharmaceutical composition for enhancing curative effect of brain glioma | 北京市神经外科研究所 | 2024-11-01 | — | — | CN | disclosed |
| US-20240239924-A1 | SYNTHESIS OF SULFONYL HALIDE TERMINATED POLYETHYLENE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-07-18 | — | — | US | disclosed |
| WO-2024059705-A1 | COMPOSITIONS AND METHODS FOR TREATING DEPRESSION IN FEMALES | SIRTSEI PHARMACEUTICALS, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| CN-116327709-A | Preparation method and application of Cu-based nano-carrier with multiple stimulus response degradability | 桂林医学院 | 2023-06-27 | — | — | CN | disclosed |
| US-20230157156-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2023-05-18 | — | — | US | disclosed |
| US-20070135481-A1 | Compositions and methods of treating retinal disease | ALDEYRA THERAPEUTICS, INC. (F/K/A ALDEXA THERAPEUTICS, INC. F/K/A NEURON SYSTEMS, INC.) | 2007-06-14 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-6103736-A | SHOWING AN INHIBITORY ACTION ON GASTRIC ACID SECRETION AND A PROTECTIVE ACTION OF GASTRIC MUCOSA; 2-(HETERO)ARYL-3-AMINOIMIDAZO-(2,1-A)ISOQUINOLINES; ANTIULCER AGENTS; | SHINNIPPON PHARMACEUTICAL INC. (JP) | 2000-08-15 | — | — | US | disclosed |
| US-6020342-A | Fused imidazo[1,2-A]pyridines | SHINNIPPON PHARMACEUTICAL, INC. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0822194-A1 | FUSED IMIDAZO 1,2-a]PYRIDINES | Shinnippon Pharmaceutical Inc. (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0593639-B1 | PYRROLIDINE AND THIAZOLIDINE DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE POULENC RORER SA (FR) | 1995-04-05 | — | — | EP | disclosed |
| EP-0593639-A1 | PYRROLIDINE AND THIAZOLIDINE DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME. | RHONE POULENC RORER SA (FR) | 1994-04-27 | — | — | EP | disclosed |
| EP-0527069-A1 | Derivatives of pyrrolidine and thiazolidine, their preparation, and pharmaceutical compositions containing them | Aventis Pharma S.A. (FR) | 1993-02-10 | — | — | EP | disclosed |
| WO-1993001167-A1 | PYRROLIDINE AND THIAZOLIDINE DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1993-01-21 | — | — | WO | disclosed |