SCHEMBL5543986

SCHEMBL5543986

CC(C)(C)c1cc2ccccc2c2c1C=CC(c1ccccc1)(c1ccccc1)O2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.33
MEN1 O00255 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17929234 0.83 ACP1 (0.34) GPR84MEN1KMT2AHSD17B10
SCHEMBL5545747 0.81 MEN1 (0.32) MEN1RECQLKMT2AHSD17B10
SCHEMBL7522579 0.80 MEN1 (0.47) GPR84MEN1RECQLKMT2A
SCHEMBL26290020 0.77 GPR35 (0.40) MEN1RECQLKMT2AHSD17B10
SCHEMBL14437373 0.77 MEN1 (0.32) GPR84MEN1RECQLKMT2A
SCHEMBL10102260 0.76 GPR84 (0.34) GPR84
SCHEMBL26290022 0.75 KDM4E (0.45) GPR84MEN1KMT2AHSD17B10
SCHEMBL7128153 0.75 PDE4D (0.40) GPR84
SCHEMBL9185542 0.74 HSD17B10 (0.33) HSD17B10
SCHEMBL7527586 0.74 MAOB (0.38) GPR84MEN1RECQLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0926146-B1 CHROMENE COMPOUNDS TOKUYAMA CORP (JP) 2003-02-12 EP claimed
EP-1312621-B1 Process for producing a photochromic cured product TOKUYAMA CORP (JP) 2007-06-06 EP disclosed
US-6864299-B1 Process for producing cured photochromic TOKUYAMA CORPORATION (JP) 2005-03-08 US disclosed
EP-1312621-A1 PROCESS FOR PRODUCING CURED PHOTOCHROMIC TOKUYAMA CORPORATION (JP) 2003-05-21 EP disclosed
EP-0926146-B1 CHROMENE COMPOUNDS TOKUYAMA CORP (JP) 2003-02-12 EP disclosed
US-6197225-B1 PHOTOCHROMIC LENS MADE OF A POLYMER OF A PHOTOCHROMIC POLYMERIZABLE COMPOSITION TOKUYAMA CORPORATION (JP) 2001-03-06 US disclosed
EP-0926146-A1 CHROMENE COMPOUNDS TOKUYAMA CORPORATION (JP) 1999-06-30 EP disclosed