SCHEMBL5544010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5538640	0.86	PTGS1 (0.53)	PTGS1PTGS2ALDH1A1CYP1A2NPC1
	SCHEMBL5544005	0.83	PTGS1 (0.50)	PTGS1PTGS2ALDH1A1CYP1A2NPC1
	SCHEMBL10263008	0.82	RAB9A (0.47)	ALDH1A1NPC1TP53RAB9ATSHR
	SCHEMBL10833110	0.80	PTGS1 (0.43)	PTGS1PTGS2ALDH1A1CYP1A2NPC1
	SCHEMBL5541456	0.79	ADORA2A (0.46)	ADORA2AADORA1NOTUMADORA2BMAPT
	SCHEMBL5536993	0.78	ALDH1A1 (0.47)	PTGS1PTGS2ALDH1A1NPC1RAB9A
	SCHEMBL5214925	0.77	MAPK13 (0.58)	PTGS1PTGS2ALDH1A1TP53RAB9A
	SCHEMBL5546758	0.76	ALDH1A1 (0.48)	PTGS1PTGS2ALDH1A1CYP1A2NPC1
	SCHEMBL10832209	0.76	ADORA2A (0.47)	ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2
	SCHEMBL10834272	0.74	RXRA (0.44)	PTGS1PTGS2ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.