SCHEMBL5544111

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5537952	0.89	NPC1 (0.45)	NPC1MAPTRAB9ALMNAMAPK1
	SCHEMBL5547563	0.88	NPC1 (0.44)	NPC1MAPTRAB9ALMNAMAPK1
	SCHEMBL6426163	0.86	NPC1 (0.50)	NPC1MAPTRAB9ALMNAMAPK1
	SCHEMBL2225521	0.83	NPC1 (0.51)	NPC1MAPTRAB9ALMNAMAPK1
	SCHEMBL5541970	0.83	DRD2 (0.55)	NPC1RAB9ALMNAHDAC1HDAC8
	SCHEMBL202513	0.81	NPC1 (0.51)	NPC1MAPTRAB9ALMNAMAPK1
	SCHEMBL27610597	0.80	NPC1 (0.45)	NPC1MAPTRAB9ALMNAMAPK1
	SCHEMBL13680927	0.80	LMNA (0.45)	NPC1MAPTRAB9ALMNAMAPK1
	SCHEMBL381503	0.79	NOTUM (0.51)	NPC1MAPTRAB9ALMNAMAPK1
	SCHEMBL12996293	0.79	NPC1 (0.50)	NPC1MAPTRAB9ALMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.