SCHEMBL55445

SCHEMBL55445

CC1(C)OB(c2ccc(N)cc2)OC1(C)C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 12/20 0.59
LIPG Q9Y5X9 12/20 0.59
CA1 P00915 4/20 0.53
CA2 P00918 4/20 0.53
CA9 Q16790 4/20 0.53
CA12 O43570 1/20 0.53
CA3 P07451 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53
CA7 P43166 1/20 0.53
CA14 Q9ULX7 1/20 0.53
CA5B Q9Y2D0 1/20 0.53
F11 P03951 2/20 0.51
F2 P00734 1/20 0.44
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
ESR2 Q92731 1/20 0.44
P4HB P07237 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium SCHEMBL31733916 0.98 LPL (0.57) LPLLIPGCA1CA2CA9
Hydrochloric Acid SCHEMBL16899373 0.98 LPL (0.57) LPLLIPGCA1CA2CA9
SCHEMBL13636816 0.89 P4HB (0.52) LPLLIPGCA1CA2CA9
SCHEMBL228212 0.88 LPL (0.71) LPLLIPGCA1CA2CA9
SCHEMBL28852276 0.86 LIPG (0.64) LPLLIPGCA1CA2CA9
SCHEMBL24246101 0.85 LPL (0.44) LPLLIPGCA1CA2CA9
SCHEMBL20644595 0.84 MAPT (0.51) LPLLIPGCA1CA2CA9
SCHEMBL24246117 0.83 LPL (0.49) LPLLIPGCA1CA2CA9
SCHEMBL17264190 0.83 LPL (0.41) LPLLIPGCA1CA2CA9
SCHEMBL24608995 0.81 LIPG (0.83) LPLLIPGCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2985 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039153-A Novel three-dimensional covalent-organic framework ligand, and preparation method and application thereof 武汉大学 2024-11-29 CN claimed
US-20230210790-A1 GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES THE JOHNS HOPKINS UNIVERSTY 2023-07-06 US claimed
CN-115926084-A Preparation method of donor-receptor type covalent organic framework membrane material and three-order nonlinear optical application 浙江工业大学 2023-04-07 CN claimed
EP-4157998-A1 GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES The Johns Hopkins University (US) 2023-04-05 EP claimed
CN-114751910-B Compound capable of inducing cell megalophage death and preparation method and application thereof 重庆文理学院 2023-02-24 CN claimed
CN-113072926-B Application of fluorescent polymer in detecting residual organic pesticide in environment 辽宁大学 2022-10-14 CN claimed
CN-115093433-A Hydrophilic organic near-infrared absorption dye and preparation method and application thereof 华南理工大学 2022-09-23 CN claimed
CN-114805761-A Pyridazinyl conjugated microporous polymer, preparation method and iodine adsorption application method 西南大学 2022-07-29 CN claimed
CN-114751910-A Compound capable of inducing cell megacyst type death and preparation method and application thereof 重庆文理学院 2022-07-15 CN claimed
CN-114656492-A Preparation method of BODIPY molecule and optical activity loaded nano-silver COF material thereof 广东药科大学 2022-06-24 CN claimed
WO-2007102126-A2 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2007-09-13 WO claimed
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY 2007-09-13 US claimed
EP-1747196-A2 SUBSTITUTED ARYL ACYLTHIOUREAS AND RELATED COMPOUNDS; INHIBITORS OF VIRAL REPLICATION Achillion Pharmaceuticals, Inc. (US) 2007-01-31 EP claimed
WO-2006083271-A2 SUBSTITUTED ARYL ACYLTHIOUREAS AND RELATED COMPOUNDS; INHIBITORS OF VIRAL REPLICATION ACHILLION PHARMACEUTICALS, INC. (US) 2006-08-10 WO claimed
US-6559310-B2 Reacting a halogen aromatic derivative at a coupling position with a diboron derivative in the presence of a Group VIII metal catalyst and a suitable base for covalently coupling organic compounds COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-05-06 US claimed
US-20020193604-A1 Aryl borates COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2002-12-19 US claimed
EP-0986541-A4 PROCESS FOR COVALENTLY COUPLING ORGANIC COMPOUNDS UTILIZING DIBORON DERIVATIVES COMMW SCIENT IND RES ORG (AU) 2002-08-14 EP claimed
US-20020032339-A1 ARYL BORATES BORON MOLECULAR LIMITED (AU) 2002-03-14 US claimed
EP-0986541-A1 PROCESS FOR COVALENTLY COUPLING ORGANIC COMPOUNDS UTILIZING DIBORON DERIVATIVES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-03-22 EP claimed
WO-1998045265-A1 PROCESS FOR COVALENTLY COUPLING ORGANIC COMPOUNDS UTILIZING DIBORON DERIVATIVES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1998-10-15 WO claimed