SCHEMBL5544514

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8036021	0.85	ESR1 (0.56)	LOXL2AGXTESR1ESR2KDM4E
	SCHEMBL8039758	0.82	LOXL2 (0.51)	LOXL2AGXTESR1ESR2KDM4E
	SCHEMBL9233691	0.82	LOXL2 (0.56)	LOXL2AGXTESR1ESR2HTR1A
	SCHEMBL4659383	0.81	LOXL2 (0.50)	LOXL2AGXTESR1ESR2KDM4E
	SCHEMBL4661924	0.81	LOXL2 (0.50)	LOXL2AGXTESR1ESR2KDM4E
	SCHEMBL7171559	0.81	ESR1 (0.59)	LOXL2AGXTESR1ESR2KDM4E
	SCHEMBL1650806	0.79	ESR1 (0.57)	LOXL2AGXTESR1ESR2MAOB
	SCHEMBL11101351	0.79	ESR1 (0.54)	LOXL2AGXTESR1ESR2KDM4E
	SCHEMBL6013090	0.78	LOXL2 (0.60)	LOXL2AGXTMAOBHTR1AHTR2B
	SCHEMBL10367978	0.78	LOXL2 (0.55)	LOXL2AGXTESR1ESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.