Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17063055 | 0.79 | ACHE (0.41) | TDP1SMN1; SMN2TP53ALDH1A1ACHE | |
| SCHEMBL29464240 | 0.79 | ACHE (0.41) | TDP1SMN1; SMN2TP53ALDH1A1ACHE | |
| SCHEMBL21741514 | 0.76 | ACHE (0.65) | CYP3A4TDP1SMN1; SMN2ALDH1A1ACHE | |
| SCHEMBL10289790 | 0.76 | ACHE (0.39) | CYP3A4TDP1TP53ALDH1A1ACHE | |
| SCHEMBL1341152 | 0.76 | CYP3A4 (0.42) | CYP3A4TDP1ALOX15SMN1; SMN2TP53 | |
| SCHEMBL7766990 | 0.75 | ACHE (0.41) | CYP3A4TDP1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL29591261 | 0.75 | ACHE (0.41) | CYP3A4TDP1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL91459 | 0.74 | ALDH1A1 (0.68) | CYP3A4TDP1ALOX15SMN1; SMN2TP53 | |
| SCHEMBL30294328 | 0.74 | ALDH1A1 (0.68) | CYP3A4TDP1ALOX15SMN1; SMN2TP53 | |
| SCHEMBL1341730 | 0.73 | CYP3A4 (0.48) | CYP3A4TDP1ALOX15SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3978021-A1 | EXPRESSION REGULATOR OF P2X7 RECEPTOR | Osaka University (JP) | 2022-04-06 | — | — | EP | disclosed |
| US-7273710-B2 | Method for screening MCH receptor antagonist/agonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-09-25 | — | — | US | disclosed |