SCHEMBL554497

SCHEMBL554497

Clc1ccc(-c2ccn(-c3ccccc3)n2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.55
MEN1 O00255 4/20 0.55
KDM4E B2RXH2 3/20 0.55
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.46
GAA P10253 2/20 0.45
HTT P42858 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
DRD2 P14416 1/20 0.44
TP53 P04637 1/20 0.44
PTPN1 P18031 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PTGS2 P35354 3/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28001364 0.93 KMT2A (0.48) KMT2AMEN1KDM4ENPC1RAB9A
SCHEMBL218118 0.87 KMT2A (0.57) KMT2AMEN1KDM4ENPC1RAB9A
Ammonia Solution, Strong SCHEMBL10418488 0.85 KMT2A (0.55) KMT2AMEN1KDM4ENPC1RAB9A
SCHEMBL13801011 0.83 HTT (0.50) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL13679138 0.82 HTT (0.65) KMT2AMEN1KDM4ENPC1RAB9A
SCHEMBL27260683 0.82 POLB (0.48) KMT2AMEN1KDM4ENPC1RAB9A
SCHEMBL27652739 0.81 ADORA2A (0.50) KMT2AMEN1KDM4ENPC1RAB9A
SCHEMBL15941989 0.81 FLT3 (0.59) KDM4ERAB9ASMN1; SMN2LMNAPTGS2
SCHEMBL2148390 0.80 ALDH1A1 (0.46) KMT2AKDM4ESMN1; SMN2HTTL3MBTL1
SCHEMBL182105 0.80 POLB (0.50) KMT2AMEN1KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090129053-A1 LIGHT-ENHANCED ELEMENT LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. (TW) 2009-05-21 US claimed
US-20070159062-A1 Light-enhanced element LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. 2007-07-12 US claimed
WO-1998025918-A1 ANALGESIC, ANTI-INFLAMMATORY AND ANTI-THROMBOSIS ESTERS OF NITRATED CYCLOALIPHATIC ALCOHOLS HOECHST MARION ROUSSEL (FR) 1998-06-18 WO claimed
CN-114057646-B Pyrazole derivative and application thereof in preparation of antitumor drugs 常州大学 2023-05-02 CN disclosed
US-20220306836-A1 PHOTOPERIODIC CONTROL OF PHYTOCHROME WITH MATERIALS Lleaf Pty Ltd (AU) 2022-09-29 US disclosed
CN-114057646-A Pyrazole derivative and application thereof in preparation of antitumor drugs 常州大学 2022-02-18 CN disclosed
EP-3924430-A1 PHOTOPERIODIC CONTROL OF PHYTOCHROME WITH MATERIALS Lleaf Pty Ltd (AU) 2021-12-22 EP disclosed
WO-2020163917-A1 PHOTOPERIODIC CONTROL OF PHYTOCHROME WITH MATERIALS Lleaf Pty Ltd (AU) 2020-08-20 WO disclosed
EP-2391705-B1 METHOD AND APPARATUS FOR CULTIVATION OF ALGAE AND CYANOBACTERIA ZERO DISCHARGE PTY LTD (AU) 2015-04-22 EP disclosed
CN-102378811-B Device for measuring the position of a moving object ZERO DISCHARGE PTY LTD 2015-04-01 CN disclosed
CN-102378811-A Apparatus and method for cultivating algae and cyanobacteria ZERO DISCHARGE PTY LTD 2012-03-14 CN disclosed
US-20120034679-A1 METHOD AND APPARATUS FOR CULTIVATION OF ALGAE AND CYANOBACTERIA Zero Discharge Pty Ltd, 2012-02-09 US disclosed
WO-2010085853-A1 METHOD AND APPARATUS FOR CULTIVATION OF ALGAE AND CYANOBACTERIA ZERO DISCHARGE PTY LTD (AU) 2010-08-05 WO disclosed
US-20090129053-A1 LIGHT-ENHANCED ELEMENT LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. (TW) 2009-05-21 US disclosed
US-20090129053-A1 LIGHT-ENHANCED ELEMENT LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. (TW) 2009-05-21 US disclosed
US-20090129053-A1 LIGHT-ENHANCED ELEMENT LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. (TW) 2009-05-21 US disclosed
US-20070159062-A1 Light-enhanced element LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. 2007-07-12 US disclosed
US-20070159062-A1 Light-enhanced element LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. 2007-07-12 US disclosed
US-20070159062-A1 Light-enhanced element LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. 2007-07-12 US disclosed
WO-1998025918-A1 ANALGESIC, ANTI-INFLAMMATORY AND ANTI-THROMBOSIS ESTERS OF NITRATED CYCLOALIPHATIC ALCOHOLS HOECHST MARION ROUSSEL (FR) 1998-06-18 WO disclosed