Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537255 | 0.72 | KDM4E (0.50) | — | |
| SCHEMBL7916406 | 0.71 | IKBKB (0.46) | LTA4HADORA2AADORA1HPGDS | |
| SCHEMBL5342853 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL30633034 | 0.68 | MEN1 (0.39) | LTA4HADORA2AADORA1HPGDS | |
| SCHEMBL30632958 | 0.68 | ADRA1A (0.36) | LTA4HADORA2AADORA1HPGDS | |
| SCHEMBL3040416 | 0.67 | NPC1 (0.46) | ADORA2AADORA1 | |
| SCHEMBL31128921 | 0.67 | APP (0.47) | — | |
| SCHEMBL7058872 | 0.65 | PIM1 (0.66) | — | |
| SCHEMBL29700510 | 0.63 | ALDH1A1 (0.34) | ADORA2AADORA1BRD4 | |
| SCHEMBL5030066 | 0.62 | LTA4H (0.39) | LTA4HADORA2AADORA1HPGDSBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805187-A1 | INHIBITORS OF HEPATITIS C VIRUS PROTEASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | Pfizer, Inc. (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006043145-A1 | INHIBITORS OF HEPATITIS C VIRUS PROTEASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2006-04-27 | — | — | WO | disclosed |