Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3521844 | 0.84 | MAT2A (0.38) | GSK3AGSK3B | |
| SCHEMBL3527204 | 0.84 | GSK3A (0.41) | GSK3AGSK3B | |
| SCHEMBL3528514 | 0.84 | GSK3B (0.33) | GSK3AGSK3B | |
| SCHEMBL5545590 | 0.83 | GSK3B (0.35) | GSK3AGSK3B | |
| SCHEMBL3529268 | 0.83 | ADORA1 (0.37) | GSK3AGSK3B | |
| SCHEMBL3521775 | 0.83 | GSK3B (0.36) | GSK3AGSK3B | |
| SCHEMBL5543505 | 0.83 | GSK3A (0.36) | GSK3AGSK3B | |
| SCHEMBL5545504 | 0.83 | GAA (0.43) | GSK3AGSK3B | |
| SCHEMBL5543665 | 0.82 | GAA (0.40) | GSK3AGSK3B | |
| SCHEMBL5543598 | 0.81 | HSD17B10 (0.43) | GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678180-B1 | SUBSTITUTED 2H-[1,2,4]TRIAZOLO 4,3-A PYRAZINES AS GSK-3 INHIBITORS | PFIZER PROD INC (US) | 2007-08-08 | — | — | EP | disclosed |