SCHEMBL5546082

SCHEMBL5546082

C=C(C)c1ccc([C](C)C)cc1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
HTT P42858 1/20 0.35
GFER P55789 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
ALDH1A1 P00352 3/20 0.33
LMNA P02545 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
GRIK2 Q13002 2/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56361 0.90 MAPT (0.40) MAPTHTTGFERHSD17B10GPR55
SCHEMBL7596929 0.87 MAPT (0.38) MAPTHTTGFERHSD17B10GPR55
SCHEMBL28660752 0.87 MAPT (0.38) MAPTHTTGFERHSD17B10GPR55
SCHEMBL1552000 0.83 ESR1 (0.38) MAPTHSD17B10ALDH1A1LMNACES2
SCHEMBL9516265 0.81 MAPT (0.44) MAPTHTTGFERHSD17B10GPR55
SCHEMBL94501 0.81 ALDH1A1 (0.52) MAPTHTTALDH1A1LMNACES2
SCHEMBL29563238 0.80 ALDH1A1 (0.35) MAPTHTTGFERHSD17B10GPR55
SCHEMBL135213 0.79 MAPT (0.60) MAPTHTTGFERHSD17B10GPR55
SCHEMBL609397 0.79 MAPT (0.33) MAPTHTTGFERHSD17B10GPR55
SCHEMBL8017963 0.78 MAPT (0.34) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0624576-B1 Monomeric aminoplasts crosslinking agents CYTEC TECH CORP (US) 2000-10-25 EP claimed
EP-0873303-B1 ETHYLENICALLY-UNSATURED 1,3-DIKETOAMIDE FUNCTIONAL COMPOUNDS, POLYMERS THEREOF AND LATEX FORMULATIONS CONTAINING THE SAME JOHNSON S C COMM MARKETS INC (US) 2000-05-03 EP claimed
EP-0340976-B1 Acrylic polymers PPG INDUSTRIES INC (US) 1995-06-28 EP claimed
EP-0304083-B1 Primerless adhesive for fiberglass reinforced polyester substrates ASHLAND OIL INC (US) 1994-03-16 EP claimed
EP-0437268-B1 Method for binding a non-woven fiber-web by using a formaldehyde-free binder composition and products manufactured therewith NAT STARCH CHEM INVEST (US) 1994-01-12 EP claimed
EP-0351534-B1 POLYFUNCTIONAL MONOMERS AND PROCESS FOR PRODUCTION THEREOF MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-05-12 EP claimed
EP-0270318-B1 MODIFIED STRUCTURAL ADHESIVES LORD CORPORATION (US) 1992-04-15 EP claimed
EP-0879224-B2 NOVEL POLY(MONOPEROXYCARBONATES) ARKEMA INC (US) 2013-12-25 EP disclosed
EP-2644769-A1 Carpets with Surfactant-Stabilised Emulsion Polymer Coating Binder Celanese International Corporation (US) 2013-10-02 EP disclosed
EP-1382596-B1 Novel poly (monoperoxycarbonates) ARKEMA INC (US) 2007-02-14 EP disclosed
EP-1382596-A1 Novel poly (monoperoxycarbonates) Atofina Chemicals, Inc. (US) 2004-01-21 EP disclosed
EP-0879224-B1 NOVEL POLY(MONOPEROXYCARBONATES) ATOFINA CHEM INC (US) 2003-10-22 EP disclosed
US-6630599-B1 Blocked derivatives of m- or p- isopropenyl- alpha , alpha -dimethylbenzyl isocyanates, comprising reacting a meta- or a para-isopropenyl-alpha, alpha-dimethylbenzyl carbamate ester with hydroxy functional blocking group, such as CYTEC TECHNOLOGY CORP. 2003-10-07 US disclosed
EP-0879224-A1 NOVEL POLY(MONOPEROXYCARBONATES) ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-11-25 EP disclosed
US-5760149-A POLYMERIZATION INITIATORS, CURING AGENTS ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-06-02 US disclosed
WO-1998007684-A1 NOVEL POLY(MONOPEROXYCARBONATES) ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-02-26 WO disclosed
EP-0437268-B1 Method for binding a non-woven fiber-web by using a formaldehyde-free binder composition and products manufactured therewith NAT STARCH CHEM INVEST (US) 1994-01-12 EP disclosed
US-5250723-A Copolymerizable monomer containing carbamate or thiocarbamate, ether and isopropenylphenyl groups; protective coatings; optical lenses; hardness; scratch, heat and chemical resistances MITSUI TOATSU CHEMICALS, INC. (JP) 1993-10-05 US disclosed
EP-0351534-B1 POLYFUNCTIONAL MONOMERS AND PROCESS FOR PRODUCTION THEREOF MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-05-12 EP disclosed
EP-0437268-A1 Method for binding a non-woven fiber-web by using a formaldehyde-free binder composition and products manufactured therewith National Starch and Chemical Investment Holding Corporation (US) 1991-07-17 EP disclosed