Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16797109 | 0.73 | RXRA (0.31) | MBOAT4 | |
| SCHEMBL26023236 | 0.73 | CYP1A2 (0.41) | ALDH1A1KMT2AMAPT | |
| SCHEMBL16797152 | 0.71 | VEGFA (0.32) | ALDH1A1 | |
| SCHEMBL16797141 | 0.70 | KMT2A (0.39) | ALDH1A1MEN1KMT2AHTTKCNH2 | |
| SCHEMBL25767325 | 0.70 | SLC6A2 (0.46) | ALDH1A1MEN1KMT2AHTTKCNH2 | |
| SCHEMBL16955539 | 0.70 | MEN1 (0.35) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL19606074 | 0.69 | ALDH1A1 (0.44) | MBOAT4ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL16952605 | 0.69 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AHTTMAPT | |
| SCHEMBL15657770 | 0.69 | MBOAT4 (0.35) | MBOAT4MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL16955538 | 0.69 | KMT2A (0.34) | ALDH1A1MEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805158-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR | Kalypsys, Inc. (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006055187-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS MODULATORS OF PPAR | KALYPSYS, INC. (US) | 2006-05-26 | — | — | WO | disclosed |