SCHEMBL5546271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5547190	0.92	KMT2A (0.50)	L3MBTL1TDP1HPGDALDH1A1MAPT
	SCHEMBL13851065	0.86	KMT2A (0.57)	L3MBTL1TDP1MAPTKDM4EHTT
	SCHEMBL5541220	0.84	TDP1 (0.54)	L3MBTL1TDP1KDM4EMEN1KMT2A
	SCHEMBL5547121	0.83	TDP1 (0.49)	TDP1ALDH1A1KDM4ENPSR1HTT
	SCHEMBL5547384	0.83	ALDH1A1 (0.55)	L3MBTL1TP53TDP1HPGDALDH1A1
	SCHEMBL5538646	0.82	TDP1 (0.47)	TDP1MAPTKDM4EHTTNPC1
	SCHEMBL5548065	0.82	KDM5A (0.49)	TDP1KDM4EHTTMEN1KMT2A
	SCHEMBL15163541	0.82	TDP1 (0.48)	L3MBTL1TDP1ALDH1A1KDM4EGAA
	SCHEMBL15163542	0.81	TDP1 (0.48)	L3MBTL1TDP1ALDH1A1MAPTKDM4E
	SCHEMBL4760071	0.81	TDP1 (0.46)	TDP1MAPTKDM4EHTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.