Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 11/20 | 0.38 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.37 |
| ▸ | GJB2 | P29033 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5545051 | 0.87 | PAX8 (0.41) | MAPK1TLR4GBA1TRPV1 | |
| SCHEMBL5545001 | 0.87 | PAX8 (0.41) | MAPK1TLR4GBA1TRPV1 | |
| SCHEMBL5540231 | 0.87 | PAX8 (0.41) | MAPK1TLR4GBA1TRPV1 | |
| SCHEMBL5544808 | 0.82 | GBA1 (0.35) | MAPK1TLR4GBA1TRPV1 | |
| SCHEMBL15355993 | 0.82 | GBA1 (0.35) | MAPK1TLR4GBA1TRPV1 | |
| SCHEMBL9233216 | 0.80 | MAPK1 (0.60) | MAPK1TLR4LY96GJB2ALDH1A1 | |
| SCHEMBL5545062 | 0.79 | TRPV1 (0.42) | MAPK1TLR4LY96GBA1TRPV1 | |
| SCHEMBL5546224 | 0.79 | TRPV1 (0.42) | MAPK1TLR4LY96GBA1TRPV1 | |
| SCHEMBL9228946 | 0.78 | MAPK1 (0.43) | MAPK1GBA1ALDH1A1THRB | |
| SCHEMBL9228937 | 0.78 | MAPK1 (0.43) | MAPK1GBA1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507427-B2 | Structural and mechanistic basis for novel compound biosynthesis using the 4-electron hexose oxidase | ACADEMIA SINICA (TW) | 2013-08-13 | — | — | US | disclosed |
| US-20120108498-A1 | STRUCTURAL AND MECHANISTIC BASIS FOR NOVEL COMPOUND BIOSYNTHESIS USING THE 4-ELECTRON HEXOSE OXIDASE | ACADEMIA SINICA (TW) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108498-A1 | STRUCTURAL AND MECHANISTIC BASIS FOR NOVEL COMPOUND BIOSYNTHESIS USING THE 4-ELECTRON HEXOSE OXIDASE | G6PD, DHRS9, CYP2C9 | MAPK1 1380/4885TLR4 810/4885LY96 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.