Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 12/20 | 0.50 |
| ▸ | RORC | P51449 | 3/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLTP | P55058 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939934 | 0.91 | RORC (0.52) | AOC3RORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3939937 | 0.91 | RORC (0.52) | AOC3RORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3930927 | 0.88 | RORC (0.54) | AOC3RORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3933160 | 0.85 | RORC (0.56) | AOC3RORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL5547039 | 0.83 | RORC (0.52) | AOC3RORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL5547036 | 0.83 | RORC (0.52) | AOC3RORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3934588 | 0.82 | AOC3 (0.54) | AOC3RORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3936254 | 0.80 | AOC3 (0.56) | AOC3RORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3941557 | 0.80 | RORC (0.52) | AOC3RORCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3931236 | 0.79 | AOC3 (0.55) | AOC3RORCPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254931-A1 | Thiazole Derivatives Having Vap-1 Inhibitory Activity | ASTELLAS PHARMA INC. (JP) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254931-A1 | Thiazole Derivatives Having Vap-1 Inhibitory Activity | VCAM1, VAPB, VAPA | AOC3 386/4885RORC 2485/4885PIK3CD 4021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.