Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | QDPR | P09417 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548707 | 0.63 | SIGMAR1 (0.42) | SIGMAR1HTR2CHRH3QDPRGABRP | |
| SCHEMBL1671185 | 0.62 | — | — | |
| SCHEMBL4789631 | 0.61 | HTR2C (0.56) | SIGMAR1HTR6HTR2AHTR2CQDPR | |
| Hydrochloric Acid SCHEMBL9958496 | 0.60 | HTR2C (0.57) | SIGMAR1HTR6HTR2AHTR2CQDPR | |
| SCHEMBL23735110 | 0.59 | SIGMAR1 (0.50) | SIGMAR1HTR6HTR2AHTR2CHRH3 | |
| Hydrochloric Acid SCHEMBL1513499 | 0.58 | HTR2C (0.53) | SIGMAR1HTR6HTR2AHTR2CQDPR | |
| SCHEMBL4790049 | 0.58 | HTR2C (0.53) | SIGMAR1HTR6HTR2AHTR2CQDPR | |
| SCHEMBL29101210 | 0.58 | HTR6 (0.39) | SIGMAR1HTR6HTR2AHTR2CHRH3 | |
| SCHEMBL4789895 | 0.57 | HTR2C (0.57) | SIGMAR1HTR6HTR2AHTR2CQDPR | |
| SCHEMBL22265048 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1835934-A2 | ENZYME MODULATORS AND TREATMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006071940-A2 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-07-06 | — | — | WO | disclosed |