SCHEMBL5548272

SCHEMBL5548272

NCCCCNCCCO.O=C(O)C(F)(F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.46
CA12 O43570 3/20 0.42
CA2 P00918 3/20 0.42
CA4 P22748 3/20 0.42
CA6 P23280 3/20 0.42
CA5A P35218 3/20 0.42
CA7 P43166 3/20 0.42
CA9 Q16790 3/20 0.42
CA14 Q9ULX7 3/20 0.42
CA5B Q9Y2D0 3/20 0.42
F13A1 P00488 2/20 0.42
CYP1A2 P05177 2/20 0.42
ALOX15 P16050 2/20 0.42
THPO P40225 2/20 0.42
CA3 P07451 2/20 0.42
CA1 P00915 1/20 0.42
CYP2C9 P11712 1/20 0.42
PKM P14618 1/20 0.42
TSHR P16473 1/20 0.42
MTOR P42345 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5551428 0.90 HDAC6 (0.44) HDAC6CA12CA2CA4CA6
Trifluoroacetic Acid SCHEMBL5548189 0.88 HDAC6 (0.54) HDAC6CA12CA2CA4CA6
Bicarbonate SCHEMBL5551073 0.82 CA12 (0.56) HDAC6CA12CA2CA4CA6
Bicarbonate SCHEMBL5552761 0.82 CA12 (0.56) HDAC6CA12CA2CA4CA6
Oxalic Acid SCHEMBL5556861 0.80 CA12 (0.54) HDAC6CA12CA2CA4CA6
Acetic Acid SCHEMBL5551560 0.78 PAOX (0.55) HDAC6CA12CA2CA4CA6
Glycolic Acid SCHEMBL5552670 0.78 ALOX15 (0.52) HDAC6CA12CA2CA4CA6
Diethanolamine SCHEMBL1832177 0.78 THRB (0.39) CA12CA2CA4CA6CA5A
Monoethanolamine SCHEMBL1835204 0.78 THRB (0.42) TSHRLMNASMN1; SMN2MAPTPMP22
SCHEMBL263795 0.78 CA12 (0.68) CA12CA2CA4CA6CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US claimed