Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5548721 | 0.89 | ALDH1A1 (0.45) | ALDH1A1MAPTCSNK1DGAAMEN1 | |
| SCHEMBL11973806 | 0.87 | MEN1 (0.42) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5782488 | 0.84 | DYRK1A (0.47) | L3MBTL1ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL5551389 | 0.81 | RXFP1 (0.47) | L3MBTL1NPSR1MAPTCSNK1DMEN1 | |
| SCHEMBL3282405 | 0.80 | SMN1; SMN2 (0.45) | ALDH1A1NPSR1MEN1KMT2AHTT | |
| SCHEMBL5548662 | 0.79 | SMN1; SMN2 (0.40) | ALDH1A1NPSR1TACR1MAPTMEN1 | |
| SCHEMBL5551904 | 0.78 | PTGS1 (0.49) | NPSR1MAPTMEN1KMT2AHTT | |
| SCHEMBL5551918 | 0.77 | TP53 (0.40) | L3MBTL1ALDH1A1NPSR1MAPTCSNK1D | |
| SCHEMBL5551875 | 0.76 | MEN1 (0.50) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5547747 | 0.74 | KIF11 (0.38) | L3MBTL1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1780211-A2 | Vanilloid receptor ligands and their use in treatments | Amgen Inc. (US) | 2007-05-02 | — | — | EP | disclosed |
| EP-1775295-A1 | Vanilloid receptor ligands and their use in treatments | Amgen Inc. (US) | 2007-04-18 | — | — | EP | disclosed |