Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329523 | 0.73 | CYP1A2 (0.50) | MAPTLMNARAB9AKDM4ENPC1 | |
| SCHEMBL2490656 | 0.73 | CYP1A2 (0.50) | ALDH1A1CASP7TDP2PDK2 | |
| SCHEMBL11950500 | 0.71 | MAPT (0.60) | MAPTLMNARAB9AKDM4ENPC1 | |
| SCHEMBL3779423 | 0.71 | MAPT (0.60) | MAPTLMNARAB9AKDM4ENPC1 | |
| SCHEMBL585777 | 0.70 | LMNA (0.43) | MAPTLMNARAB9AKDM4ENPC1 | |
| Ammonia Solution, Strong SCHEMBL28721468 | 0.69 | — | — | |
| SCHEMBL2616913 | 0.68 | TDP2 (0.54) | MAPTLMNARAB9AKDM4ENPC1 | |
| SCHEMBL5022423 | 0.68 | CYP2A6 (0.54) | MAPTLMNARAB9AKDM4ENPC1 | |
| SCHEMBL12891155 | 0.67 | RAB9A (0.61) | MAPTLMNARAB9AKDM4ENPC1 | |
| SCHEMBL807459 | 0.66 | MAPT (0.72) | MAPTLMNARAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1835934-A2 | ENZYME MODULATORS AND TREATMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006071940-A2 | ENZYME MODULATORS AND TREATMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-07-06 | — | — | WO | disclosed |