Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549348 | 0.84 | — | — | |
| SCHEMBL5549269 | 0.67 | SMN1; SMN2 (0.33) | KDM4EALDH1A1HPGD | |
| SCHEMBL21718992 | 0.59 | — | — | |
| SCHEMBL21720652 | 0.59 | — | — | |
| SCHEMBL13148356 | 0.59 | GLS (0.41) | ALDH1A1HPGD | |
| SCHEMBL12621275 | 0.57 | PARP1 (0.37) | HPGD | |
| SCHEMBL21954968 | 0.57 | ALDH1A1 (0.43) | KDM4EJAK2ALDH1A1LMNAHPGD | |
| SCHEMBL21721162 | 0.56 | SMN1; SMN2 (0.33) | HPGD | |
| SCHEMBL21720941 | 0.56 | P2RX7 (0.32) | — | |
| SCHEMBL21720796 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678180-B1 | SUBSTITUTED 2H-[1,2,4]TRIAZOLO 4,3-A PYRAZINES AS GSK-3 INHIBITORS | PFIZER PROD INC (US) | 2007-08-08 | — | — | EP | disclosed |