Sugi Predict

Sugi Predict / Compounds / SCHEMBL5550176

SCHEMBL5550176

SCHEMBL5550176

CCc1ccc(N)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.50
▸ TAAR1 Q96RJ0 1/20 0.43
▸ NOS3 P29474 1/20 0.42
▸ NOS1 P29475 1/20 0.42
▸ NOS2 P35228 1/20 0.42
▸ TRPA1 O75762 1/20 0.41
▸ CA12 O43570 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA4 P22748 1/20 0.41
▸ CA6 P23280 1/20 0.41
▸ CA5A P35218 1/20 0.41
▸ CA7 P43166 1/20 0.41
▸ CA9 Q16790 1/20 0.41
▸ CA14 Q9ULX7 1/20 0.41
▸ CA5B Q9Y2D0 1/20 0.41
▸ CYP1A2 P05177 1/20 0.40
▸ CYP2A6 P11509 1/20 0.40
▸ NPC1 O15118 2/20 0.39
▸ RAB9A P51151 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20226499 0.83 SKP2 (0.48) ALDH1A1TAAR1CA12CA1CA2
SCHEMBL7203265 0.82 NPC1 (0.46) ALDH1A1TAAR1NOS3NOS1NOS2
SCHEMBL29739227 0.82 NPC1 (0.46) ALDH1A1TAAR1NOS3NOS1NOS2
SCHEMBL864771 0.81 ALDH1A1 (0.54) ALDH1A1TAAR1CA12CA1CA2
SCHEMBL5991787 0.79 SKP2 (0.65) ALDH1A1CA1CA2NPC1RAB9A
SCHEMBL8765042 0.79 ALDH1A1 (0.52) ALDH1A1TAAR1CA12CA1CA2
SCHEMBL3360093 0.79 ALDH1A1 (0.52) ALDH1A1TAAR1CA12CA1CA2
SCHEMBL30361149 0.78 NOS3 (0.46) ALDH1A1TAAR1NOS3NOS1NOS2
SCHEMBL126441 0.78 TRPA1 (0.46) ALDH1A1TAAR1NOS3NOS1NOS2
SCHEMBL841623 0.78 NOS3 (0.46) ALDH1A1TAAR1NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121570571-A Sea cucumber peptide for promoting male function improvement and preparation method thereof 福建大众健康生物科技有限公司 2026-02-27 — — CN claimed
CN-113396137-A Method for producing 1,1, 1-trifluoro-2, 2-bisarylethane, and 1,1, 1-trifluoro-2, 2-bisarylethane 中央硝子株式会社 2021-09-14 — — CN claimed
CN-121570571-A Sea cucumber peptide for promoting male function improvement and preparation method thereof 福建大众健康生物科技有限公司 2026-02-27 — — CN disclosed
CN-121570571-A Sea cucumber peptide for promoting male function improvement and preparation method thereof 福建大众健康生物科技有限公司 2026-02-27 — — CN disclosed
EP-4313981-B1 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS PFIZER (US) 2026-02-25 — — EP disclosed
US-20250263411-A1 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS PFIZER INC. (US) 2025-08-21 — — US disclosed
CN-117561255-A 3, 4-dihydro-2, 7-naphthyridine-1, 6 (2H, 7H) -dione compounds as MEK inhibitors 辉瑞公司 2024-02-13 — — CN disclosed
EP-4313981-A1 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS Pfizer Inc. (US) 2024-02-07 — — EP disclosed
US-20240002384-A1 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS PFIZER INC. (US) 2024-01-04 — — US disclosed
US-11802127-B2 3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-diones as MEK inhibitors PFIZER INC. (US) 2023-10-31 — — US disclosed
CN-116396261-A Fluoro-spiro-aryl hole transport material for perovskite solar cell, and preparation method and application thereof 宁波维海云光电科技有限公司 2023-07-07 — — CN disclosed
CN-101593852-A Multibranched polymers and manufacture method thereof NIPPON SODA CO (JP) 2009-12-02 — — CN disclosed
US-7488748-B2 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists RANBAXY LABORATORIES LIMITED (IN) 2009-02-10 — — US disclosed
US-7488748-B2 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists RANBAXY LABORATORIES LIMITED (IN) 2009-02-10 — — US disclosed
WO-2008012344-A1 NAPHTHALENE DERIVATIVES USED AS EP4 RECEPTOR AGONISTS GLAXO GROUP LIMITED (GB) 2008-01-31 — — WO disclosed
US-7273877-B2 5-substituted-4-[(substituted phenyl) amino]-2-pyridone derivatives WARNER-LAMBERT COMPANY, LLC (US) 2007-09-25 — — US disclosed
WO-2002000649-A9 SUBSTITUTED QUINAZOLINE DERIVATIVES AND THEIR USE AS INHIBITORS ASTRAZENECA AB (SE) 2007-09-20 — — WO disclosed
CN-101001887-A Multi-branched polymer and method for producing same NIPPON SODA CO (JP) 2007-07-18 — — CN disclosed
US-20050026964-A1 5-Substituted-4-[(substituted phenyl) amino]-2-pyridone derivatives WARNER-LAMBERT COMPANY LLC 2005-02-03 — — US disclosed
WO-2005000818-A1 5-SUBSTITUTED-4-`(SUBSTITUTED PHENYL)!AMINO!-2-PYRIDONE DEVIATIVES FOR USE AS MEK INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2005-01-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240002384-A1 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS NRAS, KRAS, BRAF ALDH1A1 1249/4885TAAR1 2752/4885NOS3 2148/4885
US-20250263411-A1 3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS NRAS, KRAS, BRAF ALDH1A1 1249/4885TAAR1 2752/4885NOS3 2148/4885
US-11802127-B2 3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-diones as MEK inhibitors NRAS, KRAS, MAPK1 ALDH1A1 701/4885TAAR1 2567/4885NOS3 1184/4885
US-20050026964-A1 5-Substituted-4-[(substituted phenyl) amino]-2-pyridone derivatives CYP3A5, CYP4B1, CYP3A4 ALDH1A1 568/4885TAAR1 2555/4885NOS3 1631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.