Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | HCK | P08631 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458486 | 0.88 | MAPT (0.61) | MAPTNPC1RAB9ALMNAKMT2A | |
| SCHEMBL5455899 | 0.88 | MAPT (0.53) | MAPTNPC1RAB9ALMNAKMT2A | |
| SCHEMBL5549880 | 0.87 | MAPT (0.52) | MAPTNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL5463537 | 0.85 | MAPT (0.59) | MAPTNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL5465394 | 0.82 | RAB9A (0.75) | MAPTNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL5457959 | 0.79 | P2RY1 (0.58) | MAPTNPC1RAB9ALMNATP53 | |
| SCHEMBL5460766 | 0.79 | RBP4 (0.67) | MAPTNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL5550238 | 0.79 | RBP4 (0.55) | MAPTNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL5454329 | 0.78 | KMT2A (0.57) | MAPTNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL5455973 | 0.78 | TRPV1 (0.51) | RAF1MAPTNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | claimed |