Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 10/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MECP2 | P51608 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459969 | 0.87 | P2RY1 (0.58) | P2RY1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL5470896 | 0.86 | P2RY1 (0.71) | P2RY1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL5470998 | 0.85 | RAB9A (0.53) | P2RY1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL5452159 | 0.83 | MAPT (0.52) | P2RY1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL5465394 | 0.82 | RAB9A (0.75) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8699365 | 0.81 | ALDH1A1 (0.58) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL5455899 | 0.80 | MAPT (0.53) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL5458486 | 0.80 | MAPT (0.61) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8703388 | 0.79 | MAPT (0.67) | MAPTRAB9AKMT2ALMNATP53 | |
| SCHEMBL5550233 | 0.79 | RAF1 (0.55) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | P2RY1 3474/4885MAPT 758/4885NPC1 1089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.