Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022969 | 0.98 | — | — | |
| SCHEMBL1058399 | 0.76 | — | — | |
| SCHEMBL1058397 | 0.76 | — | — | |
| SCHEMBL25177971 | 0.74 | NAPRT (0.45) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL18143575 | 0.72 | KDM4E (0.52) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL28337066 | 0.71 | — | — | |
| SCHEMBL11287397 | 0.71 | ESR1 (0.31) | TSHRNAPRTALDH1A1HPGDKMT2A | |
| SCHEMBL5550856 | 0.66 | ALDH1A1 (0.42) | TDP1LMNAL3MBTL1ALDH1A1HPGD | |
| Carbamic Acid SCHEMBL474690 | 0.63 | CASP1 (0.42) | KDM4ELMNAALDH1A1KMT2AKMO | |
| SCHEMBL698657 | 0.62 | KDM4E (0.52) | KDM4EALOX15TSHRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632297-A | Docetaxel side chain 2'-derived novel taxanes antitumor compound as well as synthesis method and application thereof | 吉林医药学院 | 2017-05-10 | — | — | CN | claimed |
| CN-106632297-A | Docetaxel side chain 2'-derived novel taxanes antitumor compound as well as synthesis method and application thereof | 吉林医药学院 | 2017-05-10 | — | — | CN | disclosed |