Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL28055270 | 0.91 | TSHR (0.56) | ACHETSHRALDH1A1SMN1; SMN2MAPT | |
| Cadaverine Tartrate SCHEMBL28066769 | 0.88 | TSHR (0.59) | TSHRALDH1A1MAPTRAB9APOLB | |
| P-Cresol SCHEMBL25273489 | 0.84 | ACHE (0.62) | ACHEALDH1A1SMN1; SMN2MAPTRAB9A | |
| P-Cresol SCHEMBL27541413 | 0.83 | ACHE (0.77) | ACHEALDH1A1SMN1; SMN2MAPTRAB9A | |
| Cadaverine Tartrate SCHEMBL9732307 | 0.81 | LMNA (0.55) | ACHETSHRALDH1A1SMN1; SMN2MAPT | |
| Cadaverine Tartrate SCHEMBL18586007 | 0.81 | LMNA (0.55) | ACHETSHRALDH1A1SMN1; SMN2MAPT | |
| Gluconic Acid SCHEMBL29209873 | 0.80 | PDE4A (0.61) | ACHETSHRALDH1A1SMN1; SMN2MAPT | |
| Glucuronic Acid SCHEMBL28944953 | 0.80 | ACHE (0.42) | ACHEALDH1A1SMN1; SMN2MAPTRAB9A | |
| P-Cresol SCHEMBL9330932 | 0.80 | ACHE (0.72) | ACHETSHRALDH1A1SMN1; SMN2MAPT | |
| P-Cresol SCHEMBL6684218 | 0.80 | ACHE (0.72) | ACHETSHRALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590602-B | Resolution refining method of racemic citalopram diol | 浙江海森药业股份有限公司 | 2022-04-05 | — | — | CN | disclosed |
| JP-2007106987-A | COMPOSITION AND THERMOSENSITIVE ADHESIVE MATERIAL | RICOH CO LTD | 2007-04-26 | — | — | JP | disclosed |