Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | UBE2I | P63279 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848196 | 0.84 | PLA2G2A (0.41) | PLA2G2AMEN1KMT2AMAPTHPGD | |
| SCHEMBL4798246 | 0.82 | PLA2G2A (0.41) | PLA2G2AMEN1KMT2AMAPTHPGD | |
| SCHEMBL23800896 | 0.82 | SLC16A3 (0.41) | MEN1KMT2AMAPTHPGDNPC1 | |
| SCHEMBL29565491 | 0.82 | SLC16A3 (0.41) | MEN1KMT2AMAPTHPGDNPC1 | |
| SCHEMBL5551024 | 0.80 | KMT2A (0.42) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL5549293 | 0.80 | MAPT (0.39) | PLA2G2AMEN1KMT2AMAPTHPGD | |
| SCHEMBL6131929 | 0.79 | KMT2A (0.39) | PLA2G2AMEN1KMT2AHPGDNPC1 | |
| SCHEMBL26290022 | 0.79 | KDM4E (0.45) | MEN1KMT2AMAPTHPGDKDM4E | |
| SCHEMBL14629672 | 0.78 | KMT2A (0.41) | MEN1KMT2AMAPTHPGDNPC1 | |
| SCHEMBL6131938 | 0.77 | DHODH (0.40) | PLA2G2AMEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975619-B1 | INTENSE COLOURING PHOTOCHROMIC 2H-NAPHTHO[1,2-b] PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LTD (GB) | 2007-01-03 | — | — | EP | disclosed |
| EP-0975619-A1 | INTENSE COLOURING PHOTOCHROMIC 2$i(H)-NAPHTHO 1,2-$i(b)]PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998042695-A1 | INTENSE COLOURING PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LIMITED (GB) | 1998-10-01 | — | — | WO | disclosed |