Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RAC1 | P63000 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5550214 | 0.87 | KMT2A (0.47) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL7777302 | 0.82 | DHODH (0.37) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL5551024 | 0.81 | KMT2A (0.42) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL1845404 | 0.79 | KMT2A (0.43) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL8509702 | 0.79 | MEN1 (0.43) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL5650444 | 0.79 | MAPT (0.38) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL5551001 | 0.78 | PLA2G2A (0.38) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL26290022 | 0.77 | KDM4E (0.45) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL7479868 | 0.75 | MEN1 (0.40) | KMT2AMEN1HCRTR1MAPTALDH1A1 | |
| SCHEMBL5549293 | 0.74 | MAPT (0.39) | KMT2AMEN1HCRTR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975619-B1 | INTENSE COLOURING PHOTOCHROMIC 2H-NAPHTHO[1,2-b] PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LTD (GB) | 2007-01-03 | — | — | EP | disclosed |