SCHEMBL5551229

SCHEMBL5551229

Cc1ccc(NC(=Cc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
KMT2A Q03164 5/20 0.56
MEN1 O00255 4/20 0.56
RAB9A P51151 7/20 0.54
MAPT P10636 7/20 0.54
NPC1 O15118 6/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
HPGD P15428 3/20 0.54
EGFR P00533 1/20 0.51
MMP1 P03956 1/20 0.51
MMP2 P08253 1/20 0.51
MMP9 P14780 1/20 0.51
NPSR1 Q6W5P4 4/20 0.51
TDP1 Q9NUW8 1/20 0.51
LMNA P02545 3/20 0.47
MAPK1 P28482 2/20 0.47
POLB P06746 2/20 0.47
KDM4E B2RXH2 1/20 0.47
HTT P42858 1/20 0.47
GAA P10253 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1492165 0.87 MAPT (0.59) ALDH1A1KMT2AMEN1RAB9AMAPT
SCHEMBL7646245 0.87 MAPT (0.59) ALDH1A1KMT2AMEN1RAB9AMAPT
SCHEMBL16564403 0.83 EGFR (0.47) ALDH1A1KMT2AMEN1RAB9AMAPT
SCHEMBL29158467 0.79 MAPT (0.79) ALDH1A1KMT2AMEN1RAB9AMAPT
SCHEMBL29158527 0.79 MAPT (0.79) ALDH1A1KMT2AMEN1RAB9AMAPT
SCHEMBL12888034 0.78 NPC1 (0.53) ALDH1A1KMT2AMEN1RAB9AMAPT
SCHEMBL10425099 0.77 MAPT (0.50) ALDH1A1KMT2AMEN1RAB9AMAPT
SCHEMBL30513147 0.77 ALDH1A1 (0.63) ALDH1A1KMT2AMEN1RAB9AMAPT
SCHEMBL6820125 0.76 HPGD (0.57) ALDH1A1KMT2AMEN1RAB9AMAPT
SCHEMBL2528717 0.75 PTGS2 (0.57) ALDH1A1KMT2AMEN1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7309552-B2 Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable RICOH COMPANY, LTD. (JP) 2007-12-18 US disclosed
US-20050266331-A1 Electrophotographic photoconductor, electrophotography, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound RICOH COMPANY, LTD. (JP) 2005-12-01 US disclosed
US-6132914-A Bisazo compound and electrophotographic photoconductor using the same RICOH COMPANY, LTD. (JP) 2000-10-17 US disclosed