Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1492165 | 1.00 | MAPT (0.59) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL5551229 | 0.87 | ALDH1A1 (0.56) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL10692191 | 0.79 | NPC1 (0.61) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL10425099 | 0.78 | MAPT (0.50) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL1637843 | 0.77 | AKR1C1 (0.45) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL1637837 | 0.77 | AKR1C1 (0.45) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL11665349 | 0.75 | MAPT (1.00) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL285343 | 0.74 | CYP19A1 (0.40) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL14482453 | 0.73 | EPHX1 (0.50) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL298945 | 0.73 | TGM2 (0.47) | MAPTKMT2AMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947561-B1 | ORGANOPOLYSILOXANE COMPOSITION | THREE BOND CO LTD (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-6235861-B1 | REACTION INHIBITOR IS ADDED TO THE COMPOSITION COMPRISING AN ALKENYLATED ORGANOPOLYSILOXANE, AN ORGANOHYDROGENPOLYSILOXANE, AND A PLATINUM CATALYST. | THREE BOND (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0947561-A1 | ORGANOPOLYSILOXANE COMPOSITION | THREE BOND CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| EP-0560311-B1 | Electrophotographic photoreceptor | KONISHIROKU PHOTO IND (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5350655-A | Conductive substrates with photosensitive layers of diols and binders | KONICA CORPORATION (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0560311-A1 | Electrophotographic photoreceptor | KONICA CORPORATION (JP) | 1993-09-15 | — | — | EP | disclosed |