Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809052 | 0.87 | SLC1A1 (0.55) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL809091 | 0.86 | SLC1A1 (0.54) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL809237 | 0.86 | SLC1A1 (0.54) | ALDH1A1CA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL5551687 | 0.86 | SLC1A1 (0.54) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL11025934 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL809238 | 0.83 | SLC1A1 (0.48) | ALDH1A1CA1CA2CA7CA9 | |
| Potassium Ion SCHEMBL809092 | 0.83 | SLC1A1 (0.48) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL31532270 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL31532269 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL22288499 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211241-B2 | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-05-01 | — | — | US | disclosed |
| US-6861043-B2 | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes | SCHERING AG (DE) | 2005-03-01 | — | — | US | disclosed |
| US-20040091426-A1 | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-05-13 | — | — | US | disclosed |
| CN-1148360-C | Intermediate for preparing cascade polymeric ligand and contrast medium | ���ֹɷݹ�˾ | 2004-05-05 | — | — | CN | disclosed |
| US-RE38329-E1 | Chelated complexes of paramagnetic metals with low toxicity | BRACCO IMAGING S.P.A. (IT) | 2003-11-25 | — | — | US | disclosed |
| US-20020187101-A1 | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes | SCHERING AG (DE) | 2002-12-12 | — | — | US | disclosed |
| CN-1377881-A | Intermediate for preparing cascade polymeric ligand and contrast medium | SCHERING AG (DE) | 2002-11-06 | — | — | CN | disclosed |
| EP-0872479-B1 | Chelated complexes of paramagnetic metals with low toxicity | BRACCO SPA (IT) | 2002-09-04 | — | — | EP | disclosed |
| US-6426059-B1 | NUCLEAR MAGNETIC RESONANCE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2002-07-30 | — | — | US | disclosed |
| EP-0836485-B1 | CASCADE POLYMER COMPLEXES | SCHERING AG (DE) | 2002-07-24 | — | — | EP | disclosed |
| EP-0703790-A1 | IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS | BRACCO S.p.A. (IT) | 1996-04-03 | — | — | EP | disclosed |
| WO-1996004259-A1 | MACROCYCLIC CHELANTS, THEIR CHELATES AND USES THEREOF IN THE DIAGNOSTIC FIELD | BRACCO S.P.A. (IT) | 1996-02-15 | — | — | WO | disclosed |
| WO-1995032741-A1 | BILE ACID CONJUGATES, DERIVATIVES THEREOF WITH METAL COMPLEXES AND RELATED USES | BRACCO S.P.A. (IT) | 1995-12-07 | — | — | WO | disclosed |
| WO-1995015319-A1 | PARAMAGNETIC CHELATES FOR NUCLEAR MAGNETIC RESONANCE DIAGNOSIS | BRACCO S.P.A. (IT) | 1995-06-08 | — | — | WO | disclosed |
| EP-0325762-B1 | Macrocyclic chelating agents and chelates thereof | BRACCO SPA (IT) | 1995-03-22 | — | — | EP | disclosed |
| WO-1994027644-A1 | IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS | BRACCO S.P.A. (IT) | 1994-12-08 | — | — | WO | disclosed |
| US-5132409-A | Derivatives of 1,4,7,10-Tetraazacyclododecane | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1992-07-21 | — | — | US | disclosed |
| EP-0440606-A1 | MACROCYCLIC CHELATING AGENTS AND CHELATES THEREOF | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1991-08-14 | — | — | EP | disclosed |
| EP-0325762-A1 | Macrocyclic chelating agents and chelates thereof | BRACCO S.p.A. (IT) | 1989-08-02 | — | — | EP | disclosed |
| WO-1989005802-A1 | MACROCYCLIC CHELATING AGENTS AND CHELATES THEREOF | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1989-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040091426-A1 | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes | ZYX, CCNY, MOK | ALDH1A1 4835/4885CA1 1192/4885CA2 838/4885 |
| US-20020187101-A1 | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes | TFPI, LYN, SYK | ALDH1A1 4854/4885CA1 3330/4885CA2 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.