Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809238 | 0.97 | SLC1A1 (0.48) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL809052 | 0.84 | SLC1A1 (0.55) | SLC1A1CA1CA2CA7CA9 | |
| Potassium Ion SCHEMBL6442452 | 0.84 | SMN1; SMN2 (0.44) | SLC1A1CA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL5551687 | 0.83 | SLC1A1 (0.54) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL809237 | 0.83 | SLC1A1 (0.54) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL5551683 | 0.83 | ALDH1A1 (0.52) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL809091 | 0.83 | SLC1A1 (0.54) | SLC1A1CA1CA2CA7CA9 | |
| Potassium Ion SCHEMBL7927849 | 0.81 | HTT (0.43) | TSHRALDH1A1FOLH1HTTSMN1; SMN2 | |
| SCHEMBL11025934 | 0.81 | ALDH1A1 (0.55) | SLC1A1CA1CA2CA7CA9 | |
| SCHEMBL31532269 | 0.79 | ALDH1A1 (0.47) | SLC1A1CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954635-A | Preparation method of 3-benzyloxy-2-chloropropionic acid potassium salt | 苏州敬业医药化工有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-101263108-B | Process for the preparation of contrast agents | BRACCO IMAGING S.P.A. (IT) | 2011-12-21 | — | — | CN | claimed |
| EP-1588998-B1 | A process for the preparation of 2-chloro-3-(phenylmethoxy)propionic acid potassium salt | BRACCO IMAGING SPA (IT) | 2011-11-30 | — | — | EP | claimed |
| EP-1948590-B1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2010-08-18 | — | — | EP | claimed |
| JP-4476486-B2 | — | — | 2010-06-09 | — | — | JP | claimed |
| US-20090306424-A1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2009-12-10 | — | — | US | claimed |
| US-7592482-B2 | Process for the preparation of contrast agents | BRACCO IMAGING S.P.A. (IT) | 2009-09-22 | — | — | US | claimed |
| US-20090118537-A1 | Process for the Preparation of Contrast Agents | BRACCO IMAGING S.P.A. (IT) | 2009-05-07 | — | — | US | claimed |
| CN-101263108-A | Process for the preparation of contrast agents | BRACCO IMAGING SPA (IT) | 2008-09-10 | — | — | CN | claimed |
| EP-1948590-A1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | Bracco Imaging S.p.A. (IT) | 2008-07-30 | — | — | EP | claimed |
| WO-2007031390-A1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2007-03-22 | — | — | WO | claimed |
| EP-1762563-A1 | Process for the preparation of contrast agents | BRACCO IMAGING S.p.A. (IT) | 2007-03-14 | — | — | EP | claimed |
| EP-1588998-A1 | A process for the preparation of 2-chloro-3-(phenylmethoxy)propionic acid potassium salt | Bracco Imaging S.p.A. (IT) | 2005-10-26 | — | — | EP | claimed |
| EP-1095009-B1 | A PROCESS FOR THE PREPARATION OF 4-CARBOXY- 5,8,11- TRIS(CARBOXYMETHYL)- 1-PHENYL- 2-OXA- 5,8,11- TRIAZATRIDECAN- 13-OIC ACID | BRACCO IMAGING SPA (IT) | 2005-06-15 | — | — | EP | claimed |
| JP-2002520305-A | — | — | 2002-07-09 | — | — | JP | claimed |
| EP-1095009-A2 | A PROCESS FOR THE PREPARATION OF 4-CARBOXY- 5,8,11- TRIS(CARBOXYMETHYL)- 1-PHENYL- 2-OXA- 5,8,11- TRIAZATRIDECAN- 13-OIC ACID | Bracco Imaging S.p.A. (IT) | 2001-05-02 | — | — | EP | claimed |
| US-6162947-A | Process for the preparation of 4-carboxy-5, 8,11-tris (carboxymethyl)-phenyl-2-oxa-5, 8 11-triazatridecan | DIBRA S.P.A. (IT) | 2000-12-19 | — | — | US | claimed |
| WO-2000002847-A2 | A PROCESS FOR THE PREPARATION OF 4-CARBOXY- 5,8,11- TRIS(CARBOXYMETHYL)- 1-PHENYL- 2-OXA- 5,8,11- TRIAZATRIDECAN- 13-OIC ACID | BRACCO S.P.A. (IT) | 2000-01-20 | — | — | WO | claimed |
| CN-119954635-A | Preparation method of 3-benzyloxy-2-chloropropionic acid potassium salt | 苏州敬业医药化工有限公司 | 2025-05-09 | — | — | CN | disclosed |
| WO-1999045968-A1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO S.P.A. (IT) | 1999-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306424-A1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | MGMT, CA14, CA4 | SLC1A1 2414/4885CA1 23/4885CA2 123/4885 |
| US-20090118537-A1 | Process for the Preparation of Contrast Agents | MGMT, CA14, CA4 | SLC1A1 2414/4885CA1 23/4885CA2 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.