Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5551921 | 0.83 | VCAM1 (0.36) | CDK1VCAM1CA2CA1CA9 | |
| SCHEMBL24717647 | 0.82 | SOS1 (0.41) | CA2CA1CA9CA5AKDM4E | |
| SCHEMBL31072738 | 0.82 | SOS1 (0.41) | CA2CA1CA9CA5AKDM4E | |
| SCHEMBL4703972 | 0.81 | CDK1 (0.40) | CDK1VCAM1CA2CA1CA9 | |
| SCHEMBL8729538 | 0.80 | CES2 (0.44) | CA2CA1CA9KDM4ESMN1; SMN2 | |
| SCHEMBL3437073 | 0.80 | CDK1 (0.40) | CDK1VCAM1CA2CA1CA9 | |
| SCHEMBL5548265 | 0.79 | CA1 (0.41) | CDK1VCAM1CA2CA1CA9 | |
| SCHEMBL8747840 | 0.78 | ABL1 (0.41) | CA2CA1CA9SMN1; SMN2POLB | |
| SCHEMBL31305185 | 0.74 | HPGD (0.40) | CA2CA1CA9KDM4ESMN1; SMN2 | |
| SCHEMBL20594412 | 0.74 | CES2 (0.40) | CA2CA1CA9KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189679-B2 | Herbicidal 3-amino-2-thiomethylbenzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-03-13 | — | — | US | disclosed |
| US-20050221988-A1 | Herbicidal 3-amino-2-thiomethylbenzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050221988-A1 | Herbicidal 3-amino-2-thiomethylbenzoylpyrazoles | DDT, ABAT, AS3MT | CDK1 2443/4885VCAM1 4865/4885CA2 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.