SCHEMBL5548265

SCHEMBL5548265

COC(=O)c1ccc(S(C)(=O)=O)c(F)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
CA5A P35218 1/20 0.41
VCAM1 P19320 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 1/20 0.41
CDK1 P06493 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
NPC1 O15118 1/20 0.39
CASP3 P42574 1/20 0.39
RAB9A P51151 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.38
MYC P01106 1/20 0.38
CA12 O43570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4700846 0.85 CA1 (0.45) CA1CA2CA9CA5AVCAM1
SCHEMBL1357981 0.82 CA1 (0.42) CA1CA2CA9CA5AVCAM1
SCHEMBL1780058 0.81 LMNA (0.39) KDM4ELMNAMYCALDH1A1
SCHEMBL25678197 0.81 KDM4E (0.45) CA1CA2CA9CA5ASMN1; SMN2
SCHEMBL8574765 0.81 VCAM1 (0.38) CA1CA2CA9CA5AVCAM1
SCHEMBL3721889 0.80 PRKDC (0.36) ALDH1A1
SCHEMBL4703905 0.79 CA2 (0.41) CA1CA2CA9CA5AVCAM1
SCHEMBL5552149 0.79 CDK1 (0.40) CA1CA2CA9CA5AVCAM1
SCHEMBL22219524 0.78 SOS1 (0.44) CA1CA2CA9CA5ASMN1; SMN2
SCHEMBL31135335 0.78 SOS1 (0.44) CA1CA2CA9CA5ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189679-B2 Herbicidal 3-amino-2-thiomethylbenzoylpyrazoles BAYER CROPSCIENCE GMBH (DE) 2007-03-13 US disclosed
US-20050221988-A1 Herbicidal 3-amino-2-thiomethylbenzoylpyrazoles BAYER CROPSCIENCE GMBH (DE) 2005-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050221988-A1 Herbicidal 3-amino-2-thiomethylbenzoylpyrazoles DDT, ABAT, AS3MT CA1 1792/4885CA2 327/4885CA9 696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.