SCHEMBL5552298

SCHEMBL5552298

CCOc1ccc(Nc2nc(NC(CO)CO)nc(N(C)C3CCN(C)CC3)n2)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
KMT2A Q03164 1/20 0.41
BRD4 O60885 2/20 0.39
SELP P16109 1/20 0.38
TYRO3 Q06418 1/20 0.38
BCL6 P41182 1/20 0.38
P2RX3 P56373 7/20 0.38
AXL P30530 2/20 0.38
RECQL P46063 1/20 0.37
APOBEC3A P31941 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
IDH2 P48735 1/20 0.37
RORC P51449 1/20 0.35
EGFR P00533 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4838872 0.92 BCL6 (0.45) MAPTMEN1LMNAKMT2ABCL6
SCHEMBL4836250 0.84 BCL6 (0.46) MAPTMEN1LMNAKMT2ABRD4
SCHEMBL4832385 0.84 BCL6 (0.44) MAPTMEN1LMNAKMT2ABCL6
SCHEMBL4840694 0.81 BCL6 (0.52) MAPTMEN1LMNAKMT2ABRD4
SCHEMBL4832441 0.81 BCL6 (0.47) MAPTMEN1LMNAKMT2ABRD4
SCHEMBL4840381 0.78 BCL6 (0.45) MAPTMEN1LMNAKMT2ABCL6
SCHEMBL4829068 0.78 BCL6 (0.46) MAPTMEN1LMNAKMT2ABCL6
SCHEMBL5435320 0.77 BCL6 (0.49) MAPTMEN1LMNAKMT2ABRD4
SCHEMBL4837087 0.76 BCL6 (0.42) LMNABCL6AXLAPOBEC3AAPOBEC3G
SCHEMBL5032222 0.76 BCL6 (0.57) MAPTMEN1LMNAKMT2ABRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169785-B2 Methods and compositions of novel triazine compounds REDDY US THERAPEUTICS, INC. (US) 2007-01-30 US disclosed
US-20040209882-A1 Methods and compositions of novel triazine compounds DR. REDDY'S LABORATORIES LTD. (IN) 2004-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040209882-A1 Methods and compositions of novel triazine compounds AREG, TGFB1, PTGIS MAPT 3539/4885MEN1 4761/4885LMNA 2238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.