SCHEMBL555255

SCHEMBL555255

CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.50
CA1 P00915 3/20 0.49
CA2 P00918 3/20 0.49
MMP2 P08253 2/20 0.49
MMP9 P14780 2/20 0.49
CA12 O43570 2/20 0.49
CA9 Q16790 2/20 0.49
MMP1 P03956 1/20 0.49
MMP3 P08254 1/20 0.49
MMP8 P22894 1/20 0.49
MMP13 P45452 1/20 0.49
GAA P10253 2/20 0.45
EPHX1 P07099 1/20 0.44
ANPEP P15144 1/20 0.41
ERAP2 Q6P179 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
HDAC4 P56524 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30191451 1.00 BTK (0.50) BTKCA1CA2MMP2MMP9
SCHEMBL555256 1.00 BTK (0.50) BTKCA1CA2MMP2MMP9
SCHEMBL1693182 1.00 BTK (0.50) BTKCA1CA2MMP2MMP9
SCHEMBL3343104 1.00 BTK (0.50) BTKCA1CA2MMP2MMP9
SCHEMBL3344958 1.00 BTK (0.50) BTKCA1CA2MMP2MMP9
SCHEMBL765453 1.00 BTK (0.50) BTKCA1CA2MMP2MMP9
SCHEMBL16125648 1.00 BTK (0.50) BTKCA1CA2MMP2MMP9
SCHEMBL1045289 1.00 BTK (0.50) BTKCA1CA2MMP2MMP9
SCHEMBL21032211 1.00 BTK (0.50) BTKCA1CA2MMP2MMP9
SCHEMBL23463705 0.98 BTK (0.49) BTKCA1CA2MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836032-A Preparation method of cis- (1S, 2R) -N-tert-butoxycarbonyl-1, 2-cyclohexanediamine 泰州葛林美克医药科技有限公司 2023-10-03 CN claimed
EP-4722196-A1 CRYSTAL OF VIRAL PROTEASE INHIBITOR AND USE Westlake Pharmaceuticals (Hangzhou) Co., Ltd. (CN) 2026-04-08 EP disclosed
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-10-23 US disclosed
EP-4613773-A2 IRAK DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-09-10 EP disclosed
EP-3731869-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-07-23 EP disclosed
CN-116836032-B Preparation method of cis- (1S, 2R) -N-tert-butoxycarbonyl-1, 2-cyclohexanediamine 泰州葛林美克医药科技有限公司 2025-07-18 CN disclosed
CN-116836032-B Preparation method of cis- (1S, 2R) -N-tert-butoxycarbonyl-1, 2-cyclohexanediamine 泰州葛林美克医药科技有限公司 2025-07-18 CN disclosed
WO-2025045761-A1 MOLECULAR GLUE DEGRADERS AND USES THEREOF MABLINK BIOSCIENCE (FR) 2025-03-06 WO disclosed
WO-2025045758-A1 ANTIBODY-DRUG CONJUGATES BASED ON MOLECULAR GLUE DEGRADERS AND USES THEREOF MABLINK BIOSCIENCE (FR) 2025-03-06 WO disclosed
EP-4512427-A1 ANTIBODY-DRUG CONJUGATES BASED ON MOLECULAR GLUE DEGRADERS AND USES THEREOF Mablink Bioscience (FR) 2025-02-26 EP disclosed
US-6794389-B2 Quinazoline derivatives and drugs NIPPON SHINYAKU CO., LTD. (JP) 2004-09-21 US disclosed
US-20040122063-A1 Ethylenediamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-24 US disclosed
US-20040087587-A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2004-05-06 US disclosed
US-20040077645-A1 Dipeptidyl aminopeptidase inhibitors; diabetes mellitus, arthritis, obesity, allograft transplantation and osteoporosis treatment BOEHRINGER INGELHEIM PHARMA GMBH & CO KG (DE) 2004-04-22 US disclosed
EP-1368349-A1 XANTHINE DERIVATIVE, PRODUCTION AND USE THEREOF AS A MEDICAMENT Boehringer Ingelheim Pharma GmbH & Co.KG (DE) 2003-12-10 EP disclosed
US-20030119855-A1 Heterocycle derivatives and drugs NIPPON SHINYAKU CO., LTD. (JP) 2003-06-26 US disclosed
EP-1306372-A1 HETEROCYCLE DERIVATIVES AND DRUGS Nippon Shinyaku Co., Ltd. (JP) 2003-05-02 EP disclosed
EP-1270557-A1 ETHYLENEDIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-01-02 EP disclosed
US-20020198205-A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-26 US disclosed
WO-2002068420-A1 XANTHINE DERIVATIVE, PRODUCTION AND USE THEREOF AS A MEDICAMENT BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-09-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 BTK 27/4885CA1 4622/4885CA2 4617/4885
US-20040087587-A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions DPP4, DPP3, DPP7 BTK 3419/4885CA1 896/4885CA2 1018/4885
US-20030119855-A1 Heterocycle derivatives and drugs OPRL1, OPRK1, OPRD1 BTK 673/4885CA1 2568/4885CA2 843/4885
US-20020198205-A1 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions DPP4, DPP3, DPP7 BTK 3419/4885CA1 896/4885CA2 1018/4885
US-20040077645-A1 Dipeptidyl aminopeptidase inhibitors; diabetes mellitus, arthritis, obesity, allograft transplantation and osteoporosis treatment DPP4, DPP3, DPP7 BTK 2285/4885CA1 1160/4885CA2 1699/4885
US-20040122063-A1 Ethylenediamine derivatives ECE1, F2, ECE2 BTK 1123/4885CA1 3944/4885CA2 3222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.