Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30191451 | 1.00 | BTK (0.50) | BTKCA1CA2MMP2MMP9 | |
| SCHEMBL555256 | 1.00 | BTK (0.50) | BTKCA1CA2MMP2MMP9 | |
| SCHEMBL1693182 | 1.00 | BTK (0.50) | BTKCA1CA2MMP2MMP9 | |
| SCHEMBL3343104 | 1.00 | BTK (0.50) | BTKCA1CA2MMP2MMP9 | |
| SCHEMBL555255 | 1.00 | BTK (0.50) | BTKCA1CA2MMP2MMP9 | |
| SCHEMBL765453 | 1.00 | BTK (0.50) | BTKCA1CA2MMP2MMP9 | |
| SCHEMBL16125648 | 1.00 | BTK (0.50) | BTKCA1CA2MMP2MMP9 | |
| SCHEMBL1045289 | 1.00 | BTK (0.50) | BTKCA1CA2MMP2MMP9 | |
| SCHEMBL21032211 | 1.00 | BTK (0.50) | BTKCA1CA2MMP2MMP9 | |
| SCHEMBL23463705 | 0.98 | BTK (0.49) | BTKCA1CA2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912720-B2 | Rigid chiral photoluminescent isosceles triangular materials | NORTHWESTERN UNIVERSITY (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912720-B2 | Rigid chiral photoluminescent isosceles triangular materials | NORTHWESTERN UNIVERSITY (US) | 2024-02-27 | — | — | US | disclosed |
| US-20220332687-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | SANOFI (FR) | 2022-10-20 | — | — | US | disclosed |
| US-20210122767-A1 | RIGID CHIRAL PHOTOLUMINESCENT ISOSCELES TRIANGULAR MATERIALS | NORTHWESTERN UNIVERSITY (US) | 2021-04-29 | — | — | US | disclosed |
| US-20180141951-A1 | FUSED HETEROAROMATIC PYRROLIDINONES | CALITHERA BIOSCIENCES, INC. | 2018-05-24 | — | — | US | disclosed |
| US-20170327497-A1 | SUBSTITUTED 6-AZA-ISOINDOLIN-1-ONE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-11-16 | — | — | US | disclosed |
| EP-3176154-A1 | BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS | Portola Pharmaceuticals, Inc. (US) | 2017-06-07 | — | — | EP | disclosed |
| US-20150272956-A1 | SUBSTITUTED XANTHINE DERIVATIVES | SUN PHARMACEUTICAL INDUSTRIES, INC. | 2015-10-01 | — | — | US | disclosed |
| EP-1577301-B1 | Antithrombotic diaminocyclohexane derivatives | DAIICHI SANKYO CO LTD (JP) | 2012-09-12 | — | — | EP | disclosed |
| US-20100099660-A1 | METHOD FOR TREATING THROMBOSIS OR EMBOLISM AND RELATED DISEASES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099660-A1 | METHOD FOR TREATING THROMBOSIS OR EMBOLISM AND RELATED DISEASES | F2, PLAT, MPL | BTK 13/4885CA1 2523/4885CA2 4508/4885 |
| US-20220332687-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | ABCG2, CYP3A43, CYP3A5 | BTK 594/4885CA1 4107/4885CA2 3325/4885 |
| US-20180141951-A1 | FUSED HETEROAROMATIC PYRROLIDINONES | SYK, ZAP70, LYN | BTK 6/4885CA1 3703/4885CA2 4062/4885 |
| US-20210122767-A1 | RIGID CHIRAL PHOTOLUMINESCENT ISOSCELES TRIANGULAR MATERIALS | PPIE, PARN, PIN1 | BTK 4217/4885CA1 3961/4885CA2 4677/4885 |
| US-11912720-B2 | Rigid chiral photoluminescent isosceles triangular materials | PPIE, PARN, PIN1 | BTK 4217/4885CA1 3961/4885CA2 4677/4885 |
| US-20150272956-A1 | SUBSTITUTED XANTHINE DERIVATIVES | XDH, HPRT1, CXCR3 | BTK 2984/4885CA1 3414/4885CA2 2666/4885 |
| US-20170327497-A1 | SUBSTITUTED 6-AZA-ISOINDOLIN-1-ONE DERIVATIVES | SYK, MYD88, BTK | BTK 3/4885CA1 4563/4885CA2 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.