SCHEMBL5553207

SCHEMBL5553207

CCCCCC(C)(C)C1=C(O)C(=O)C(C)=CC1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 17/20 0.38
MPEG1 Q2M385 11/20 0.38
XIAP P98170 2/20 0.38
GPR84 Q9NQS5 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
PTGES O14684 1/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
MAPK1 P28482 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 1/20 0.38
KAT2B Q92831 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5553205 0.78 MEN1 (0.37) XIAPKDM4EMEN1USP2ALDH1A1
SCHEMBL8079257 0.68 CNR2 (0.44) ALOX5MPEG1CNR1CNR2
SCHEMBL17123718 0.67 ALOX5 (0.73) ALOX5MPEG1XIAPGPR84KDM4E
SCHEMBL2137325 0.66 ALDH1A1 (0.48) XIAPKDM4EMEN1USP2ALDH1A1
SCHEMBL9771507 0.66 CNR2 (0.46) ALOX5MPEG1XIAPGPR84CNR1
SCHEMBL11415223 0.65 CNR2 (0.44) ALOX5CNR1CNR2
SCHEMBL10938594 0.61 CNR2 (0.58) CNR1CNR2
SCHEMBL126588 0.60 CNR1 (0.49) KDM4EALDH1A1MAPTALOX15CNR1
SCHEMBL5536622 0.60 XIAP (0.68) ALOX5MPEG1XIAPGPR84KDM4E
SCHEMBL6244568 0.60 CNR1 (0.48) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7160658-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2007-01-09 US disclosed
US-6936388-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2005-08-30 US disclosed
US-20050170272-A1 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2005-08-04 US disclosed
US-20030077531-A1 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2003-04-24 US disclosed