SCHEMBL5553205

SCHEMBL5553205

CC1=CC(=O)C(C(C)(C)CC(C)(C)C)=C(O)C1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.37
ALDH1A1 P00352 3/20 0.37
MAPT P10636 3/20 0.37
MAPK1 P28482 3/20 0.37
BLM P54132 3/20 0.37
KMT2A Q03164 3/20 0.37
KDM4E B2RXH2 2/20 0.37
RECQL P46063 2/20 0.37
USP2 O75604 2/20 0.37
GAA P10253 2/20 0.37
NPC1 O15118 1/20 0.37
POLB P06746 1/20 0.37
THRB P10828 1/20 0.37
RAB9A P51151 1/20 0.37
TXNRD1 Q16881 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SHBG P04278 1/20 0.35
TP53 P04637 2/20 0.33
CYP1A2 P05177 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5553207 0.78 ALOX5 (0.38) MEN1ALDH1A1MAPTMAPK1KMT2A
SCHEMBL2137325 0.71 ALDH1A1 (0.48) MEN1ALDH1A1MAPTMAPK1BLM
SCHEMBL755506 0.71 ALDH1A1 (0.48) MEN1ALDH1A1MAPTMAPK1BLM
SCHEMBL10606301 0.68 ALDH1A1 (0.50) MEN1ALDH1A1MAPTMAPK1BLM
SCHEMBL7023519 0.68 CYP2C19 (0.33) MEN1ALDH1A1MAPTMAPK1BLM
SCHEMBL19267399 0.66 MAPK1 (0.34) MEN1ALDH1A1MAPTMAPK1BLM
SCHEMBL7020215 0.64 CYP2C19 (0.33) MEN1ALDH1A1MAPTMAPK1BLM
SCHEMBL19178025 0.64 ALDH1A1 (0.33) MEN1ALDH1A1MAPTMAPK1BLM
SCHEMBL7654732 0.64 PTPRC (0.30)
SCHEMBL7108805 0.62 SHBG (0.37) ALDH1A1MAPTKMT2ANPSR1SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7160658-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2007-01-09 US disclosed
US-6936388-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2005-08-30 US disclosed
US-20050170272-A1 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2005-08-04 US disclosed
US-20030077531-A1 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2003-04-24 US disclosed