Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643784 | 0.91 | ALDH1A1 (0.36) | AGTR1AGTR2ALDH1A1HPGDTSHR | |
| SCHEMBL5557234 | 0.90 | GABRP (0.42) | ALDH1A1TSHRRAB9AMEN1KMT2A | |
| SCHEMBL9642917 | 0.87 | RAB9A (0.40) | ALDH1A1HPGDTSHRNPC1RAB9A | |
| SCHEMBL9642897 | 0.86 | MEN1 (0.37) | ALDH1A1HPGDTSHRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9528440 | 0.85 | RAB9A (0.39) | ALDH1A1HPGDTSHRNPC1RAB9A | |
| SCHEMBL10441533 | 0.83 | GABRP (0.42) | ALDH1A1TSHRMEN1KMT2AGAA | |
| SCHEMBL9644276 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HPGDTSHRNPC1RAB9A | |
| SCHEMBL9643713 | 0.82 | ALDH1A1 (0.34) | ALDH1A1HPGDTSHRNPC1RAB9A | |
| SCHEMBL10268826 | 0.81 | NPC1 (0.46) | ALDH1A1HPGDNPC1RAB9AKDM4E | |
| SCHEMBL9643993 | 0.81 | GABRP (0.43) | ALDH1A1TSHRMEN1KMT2AGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
| US-5136042-A | PROCESS FOR THE PREPARATION OF THIAZOLECARBOXYLIC ACID CHLORIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-08-04 | — | — | US | disclosed |
| EP-0377750-A1 | PROCESS FOR PREPARING THIAZOLECARBOXYLIC ACID CHLORIDES | MITSUI CHEMICALS, INC. (JP) | 1990-07-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | AGTR1 1723/4885AGTR2 2270/4885ALDH1A1 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.